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    ⚠ Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Pivoxazepam Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data
    • 27 combo interactions documented

    Summary

    Pivoxazepam is a depressant benzodiazepine. Reported effects include euphoria, anxiety suppression, muscle relaxation, and compulsive redosing. Limited data is available on its dosage and safety profile.

    Effect Profile

    class estimate

    Scores (0–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • No reports exist for this substance. Its effect list is the one shared by 12 other substances of the same class, so the scores below describe the class, not this compound.
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Benzodiazepine 7.6
    Intense 8/10

    Strong anxiolysis and euphoria with moderate cognitive impairment, mild sedation

    Anxiolysis ×3
    10
    anxiety suppression anxiolytic reduced anxiety muscle relaxation
    Sedation / Relaxation ×2
    5
    sedation muscle relaxation
    ⚠ Motor / Cognitive Impairment ×1
    7
    motor control loss amnesia double vision
    Euphoria / Mood Lift ×1
    10
    cognitive euphoria euphoria physical euphoria disinhibition

    Tolerance

    Build-up develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
    Reset Falls after you stop, at a rate that varies from person to person. If you've been using regularly, cut down gradually with medical help rather than stopping suddenly.

    No tolerance chart. Our decay curves for these drugs were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    How fast tolerance to these drugs fades after a break has not been measured well enough to draw, so don't count on a dose you used to take still being safe: after time off, start with a much smaller amount and don't use alone. Mixing sedatives with each other, with alcohol or with opioids sharply raises the risk of a fatal overdose. If you've been using regularly, don't stop suddenly: withdrawal from benzodiazepines, alcohol or GHB/GBL can cause seizures or delirium, so get medical help to cut down gradually.

    Sources: FRANK: benzodiazepines · Alcohol and Drug Foundation: GHB · FDA 2020: benzodiazepine boxed warning · FDA 2019: gabapentinoids and breathing · NHS: alcohol use disorder

    Effects

    Positive
    Negative
    Neutral
    Positive
    Negative
    Positive
    Negative
    Neutral

    Combinations

    Cross-Check Pivoxazepam with another substance

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