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    PMMA

    Aliases: 4-mma, Methyl-ma

    Summary PsychonautWiki

    para-Methoxymethamphetamine (also known as 4-methoxymethamphetamine, 4-MeOMA, inaccurately as "4-MMA" (which should instead be reserved for 4-MMA (4-MeMA) instead) and more commonly as PMMA) is a highly dangerous and toxic synthetic substance of the amphetamine class that is closely related to PMA. Like PMA, it is known for producing extremely dangerous, life-threatening side effects. At lower dosages, its effects are somewhat different from PMA, with reduced tendency to cause severe hyperthermia while producing more entactogenic effects that can be mistaken for MDMA (although at higher dosages it does have the same risk as PMA).

    Perspectives

    “One hour into it, my pulse was up over 100, and I was compulsively yawning. There was some eye muscle disturbance, a little like the physical side of MDMA, but there was none of its central effects. But all the hints of the cardiovascular are there. By the fourth hour, I am pretty much back to baseline, but the yawning is still very much part of it. I might repeat this, at the same level, but with continuous close monitoring of the body.”

    Dose Information PsychonautWiki

    ROA Light Common Strong Heavy
    Oral - 100-120mg - -
    Light Common Strong Heavy

    Effect Profile

    1 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 4.3
    Moderate 4/10

    Strong euphoria with moderate stimulation, mild sensory enhancement

    Empathy / Social Openness ×3
    0
    Euphoria / Mood Elevation ×2
    9
    physical euphoria euphoria cognitive euphoria
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    5
    tactile enhancement increased libido
    Stimulant 6.2
    Strong 6/10

    Strong euphoria and anxiety/jitters with moderate stimulation and focus

    Stimulation / Energy ×3
    6
    stimulation wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    10
    physical euphoria euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    6
    analysis enhancement thought acceleration motivation enhancement
    Anxiety / Jitters ×1
    10
    anxiety increased heart rate teeth grinding vasoconstriction

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 12d Baseline ~21d

    Effects

    Positive
    • Stimulation
    • Physical euphoria
    Negative
    • Increased heart rate
    • Vasoconstriction
    • Pupil dilation
    • Teeth grinding
    • Increased perspiration
    • Nausea
    • Insomnia
    Neutral
    • Decreased appetite
    Positive
    • Alertness enhancement
    • Wakefulness
    • Euphoria
    • Analysis enhancement
    • Cognitive euphoria
    • Motivation enhancement
    Negative
    • Anxiety
    Neutral
    • Talkativeness
    • Time distortion
    • Thought acceleration
    Positive
    • Increased music appreciation
    • Tactile enhancement
    • Increased libido
    • Pattern recognition enhancement
    Negative
    • Light sensitivity
    • Appetite suppression
    • Dehydration
    • Disinhibition
    Neutral
    • Tactile intensification
    • Drifting

    Combinations TripSit

    PiHKAL / TiHKAL Shulgin

    PiHKAL #130: METHYL-MA

    “One hour into it, my pulse was up over 100, and I was compulsively yawning. There was some eye muscle disturbance, a little like the physical side of MDMA, but there was none of its central effects. But all the hints of the cardiovascular are there. By the fourth hour, I am pretty much back to baseline, but the yawning is still very much part of it. I might repeat this, at the same level, but with continuous close monitoring of the body.”

    — Alexander Shulgin, PiHKAL (with 110 mg)

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