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    Disclaimer
    NEVER swallow poppers — a single small bottle can be fatal, and swallowing is now the most common way people are poisoned by them. NEVER combine with erectile-dysfunction drugs (Viagra, Cialis, Levitra): blood pressure can crash. That risk lasts 24 hours after Viagra or Levitra and 48 hours after Cialis, long after the pill stops working.

    Poppers Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data
    • duration data present
    • toxicity data (PsychonautWiki)

    Aliases: Alkyl nitrites, Amyl nitrite, Isopropyl nitrite, Isobutyl nitrite, Butyl nitrite, Amyl, Amyls, Rush, Super Rush, Gold Rush, Jungle Juice, Amsterdam, Liquid Gold, Locker Room, Snappers, Room odouriser

    Summary PsychonautWiki

    Poppers are alkyl nitrites — volatile liquids inhaled from the bottle for a brief, intense rush. They are vasodilators rather than classical intoxicants: they relax smooth muscle throughout the body, which is why the effect is a head rush, facial flushing, a pounding heart and relaxation of the anal and vaginal sphincters, and why it is over in minutes. Effects begin within seconds and are gone in one to five. European products have mostly contained isopropyl nitrite since isobutyl nitrite was banned as a carcinogen in 2007. Two things carry nearly all of the risk. Poppers must never be swallowed — a single small bottle can be lethal, and swallowing is now the more common way people are poisoned by them. And they must never be combined with erectile-dysfunction drugs such as Viagra or Cialis, a combination named as an absolute contraindication on the drugs’ own labelling.

    Dose Information PsychonautWiki

    Dose basis. There is no dose ladder for poppers and none can be built: the substance is inhaled from the bottle until it takes effect, and no source anywhere states a recreational dose in milligrams or millilitres. What harm reduction services publish instead is a duration heuristic — TripSit and CAHMA both advise no more than about five seconds per inhalation, and Erowid describes four to six inhalations as typical. Strength varies between brands and between batches, and an opened bottle degrades. The after-effects row covers the physiological tail — flushing, headache and a fast heart rate outlast the subjective effect.

    Onset, Duration & After-effects PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Inhaled 10-30 sec <1-2 min 1-3 min 5-10 min 1-5 min

    Add missing routes to PsychonautWiki Journal

    The PsychonautWiki Journal app already has Poppers, but its built-in entry carries no dose or duration data at all. Here are the routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

    Dose & duration (reference)
    Poppers: routes the PsychonautWiki Journal app is missing
    Source: SubstanceSearch (substancesearch.com)
    
    
    Inhaled duration: onset 10-30s · peak <1-2m · offset 1-3m · total 1-5m · after-effects 5-10m
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up minimal; tolerance to the head rush within a single session
    Reset minutes to hours

    Effects Erowid

    Aggregated from 23 Erowid experience reports

    Positive Effects 7

    Color Enhancement 30.4% 70%
    Euphoria 30.4% 70%
    Anxiety Suppression 26.1% 70%
    Empathy 21.7% 70%
    Stimulation 17.4% 70%
    Music Enhancement 13.0% 70%
    Sedation 13.0% 70%

    Adverse Effects 2

    Headache 30.4% 70%
    Increased Heart Rate 13.0% 70%

    Combinations

    Cross-Check Poppers with another substance

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