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    PRO-LAD molecular structure

    PRO-LAD Stats & Data

    Psychedelic Research-chemical
    N-propylnorlsd 6-propyl-6-nor-lsd
    PubChem CID 44457803
    NPS DataHub
    MW351.49
    FormulaC22H29N3O
    CAS65527-63-1
    IUPAC(8β)-''N,N''-Diethyl-6-propyl-9,10-didehydroergoline-8-carboxamide
    SMILESCCCN1CC(C=C2C1Cc1cnc3cccc2c13)C(=O)N(CC)CC
    InChIKeyHZKYLVLOBYNKKM-OXQOHEQNSA-N
    2020/5.2 Δ9 10-Ergolene; 2021/5.2 Δ9 10-Ergolene; 2022/5.2 Δ9 10-Ergolene
    Chemical Class Lysergamide
    Psychoactive Class Psychedelic

    Receptor Profile

    Receptor Actions

    Agonists
    5-HT2A receptor partial agonist

    Subjective Effects

    Physical
    • Bodily control enhancement
    • Nausea
    • Pupil dilation
    • Spontaneous tactile sensations
    • Stimulation
    • Tactile enhancement
    Cognitive
    • Analysis enhancement
    • Conceptual thinking
    • Creativity enhancement
    • Delusions
    • Emotion enhancement
    • Immersion enhancement
    • Memory suppression
    • Ego death
    • Mindfulness
    • Novelty enhancement
    • Personal bias suppression
    • Spirituality enhancement
    • Thought acceleration
    • Thought disorganization
    • Thought loops
    • Time distortion
    • Unity and interconnectedness
    • Wakefulness
    Sensory
    Auditory
    • Enhancements
    • Distortions
    • Hallucinations
    Visual · Distortions
    • Drifting: (melting, breathing, morphing and flowing)
    • Colour shifting
    • Depth perception distortions
    • Perspective distortions
    • Symmetrical texture repetition
    • Tracers
    Visual · Enhancements
    • Colour enhancement
    • Pattern recognition enhancement
    • Visual acuity enhancement
    Visual · Hallucinatory States
    • Transformations
    • Internal hallucinations: (autonomous entities; settings, sceneries, and landscapes; alterations in perspective and scenarios and plots)

    Forked from Subjective Effect Documentation work by Josie Kins, August 2016. Via dose.wiki (CC0).

    Toxicity

    PsychonautWiki

    The toxicity and long-term health effects of recreational PRO-LAD do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because PRO-LAD is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried PRO-LAD suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance.

    Addiction & dependence

    While no formal studies have been conducted, PRO-LAD is likely not habit-forming and it is reasonable to speculate that the desire to use it can actually decrease with repeated administratino. As with most psychedelics, it likely possesses what is considered an intrinsic, self-regulating aspect to it. Tolerance to the effects of PRO-LAD is built almost immediately after ingestion.

    Effect Profile

    Curated
    Psychedelic 7.2

    Strong visuals with moderate headspace, mild auditory effects and body load

    Visual Intensity×3
    9
    Headspace Depth×3
    7
    Auditory Effects×1
    4
    Body Load / Somatic Effects×1
    4
    Based on reports from:
    TiHKAL TiHKAL #51: PRO-LAD Erowid Experience Reports PsychonautWiki PRO-LAD

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    LSD
    90% ●○○
    1P-LSD
    90% ●○○
    AL-LAD
    90% ●○○
    ETH-LAD
    90% ●○○
    ALD-52
    90% ●○○

    Legal Status

    Country Status Notes
    Austria PRO-LAD is technically not illegal but it may fall in the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich) as an analogue of LSD.
    Germany PRO-LAD is controlled under the NpSG ( New Psychoactive Substances Act ) as of July 18, 2019. Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.
    Latvia PRO-LAD is illegal in Latvia. Although it isn't officially scheduled, it is controlled as an LSD structural analog due to an amendment made on June 1, 2015.
    Switzerland PRO-LAD is illegal in Switzerland as of December 2015.
    United Kingdom On June 10, 2014, the United Kingdom Advisory Council on the Misuse of Drugs (ACMD) recommended that PRO-LAD be specifically named in the UK Misuse of Drugs Act as a class A drug despite not identifying it as ever having been sold or any harm associated with its use. The UK Home office accepted this advice and announced a ban of the substance to be enacted on 6 January 2015 as part of The Misuse of Drugs Act 1971 (Amendment) (No. 2) Order 2014.

    References

    Data Sources

    Cited References

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