Summary
Pregn-4-ene-3,20-dione, also known as Progesterone or P4 is a steroid sex hormone of the progestogen class. It occurs naturally and is the bodies major progestogen.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 100-200mg | 200-400mg | 400-600mg | 600mg+ |
| Rectal | 100-200mg | 200-400mg | 400-600mg | 600mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | After Effects |
|---|---|---|
| Oral | 30-60 min | 4-6 hrs |
| Rectal | - | 6-12 hrs |
Tolerance
Build-up
develops over 1–4 weeks of regular use
Reset
days to weeks depending on duration of use
Effects
Positive
Negative
- Motor impairment
- Mild fatigue
- Headache
- Sedation
- Dry joints
- Creaky ligaments
- Reduced water retention
- Increased vascularity
- Hot flashes
- Night sweats
Positive
- Reduced anxiety
- Anxiety suppression
- Dream potentiation
- Enhanced dream recall
Negative
- Brain fog
- Irritability
- Elevated aggression/drive
- Libido swings
- Mood volatility
- Mood changes
Positive
- Increased music appreciation
- Color enhancement
- Tactile enhancement
Negative
- Decreased libido
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Dulled perception
- Softening of skin