Propofol
Aliases: Diprivan, Milk-of-amnesia
Summary
A very short acting sedative that is usually given at the start of general anesthesia, and for maintenance of the prior. It should never be used outside of a medical setting. With that in mind, if you do plan to use this drug recreational, please have a very experienced friend with you that has the skills to insert a cannula, and monitor you very closely.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Intravenous | 10-30mg | 30-60mg | 60-100mg | 100mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak |
|---|---|---|
| Intravenous | 0-2 min | 10-20 min |
Tolerance
Build-up
develops over 1–4 weeks of regular use
Reset
days to weeks depending on duration of use
Tolerance Decay
Full tolerance
3d
Half tolerance
8d
Baseline
~14d
Effects
Aggregated from 16 Erowid experience reports
Positive Effects 4
Sedation
50.0%
70%
Euphoria
37.5%
70%
Stimulation
25.0%
70%
Anxiety Suppression
18.8%
70%
Adverse Effects 2
Confusion
25.0%
70%
Memory Suppression
25.0%
70%
Propofol's nerd page
Pharmacology, chemical data, effect profiles, and more
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