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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Proscaline

    Aliases: P, 4-propoxy-3,5-dmpea

    Categories

    Proscaline structure

    Summary TheDrug.Wiki TripSit PsychonautWiki

    Proscaline is a lesser-known mescaline analog approximately five to seven times more potent than mescaline. The substance has minimal research into its pharmacology, toxicity, and long-term effects. Use a precise milligram scale for accurate dosing. Notable findings include higher potency at 5-HT2C receptors compared to 5-HT2A/2B receptors. It is controlled in Germany, Switzerland, and the United Kingdom but remains unscheduled in the United States.

    Perspectives

    “Proscaline dulled my sense of pain and made the other senses really sharp. Everything felt really soft, and clean and clear. I could feel every hair my hand was touching. I felt so relaxed and at ease. I know that under the appropriate circumstances, this material would lead to uninhibited eroticism.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 15-30mg 30-40mg 40-60mg 60mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-60 min 1-2 hrs 2-4 hrs 3-5 hrs 3-5 hrs 360-0 min

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7โ€“14 days for partial reset; full reset may take weeks โ€” tolerance loss greatly increases overdose risk

    Effects TheDrug.Wiki TripSit

    Positive
    • Physical euphoria
    • Stimulation
    • Mental/physical stimulation
    Negative
    • Bodily pressures
    • Nausea
    • Pupil dilation
    • Restlessness
    • Sweating/chills
    • Muscle tension
    • Insomnia
    Neutral
    • Increased body temperature
    • Decreased appetite
    Positive
    • Conceptual thinking
    • Analysis enhancement
    • Emotion enhancement
    • Euphoria
    • Wakefulness
    • Empathy
    • Insight
    Negative
    • Confusion
    Neutral
    • Time distortion
    • Change in perception
    • Ego softening
    Positive
    • Colour enhancement
    • Pattern recognition enhancement
    • Visual acuity enhancement
    • Colour shifting
    • Tracers
    • Increased music appreciation
    • Brightened colour
    • Enhanced tactile sensation
    Negative
    Neutral
    • Drifting
    • Symmetrical texture repetition
    • After images
    • Closed/Open eye visuals

    Combinations TripSit

    PiHKAL / TiHKAL Shulgin

    PiHKAL #140: P

    “Proscaline dulled my sense of pain and made the other senses really sharp. Everything felt really soft, and clean and clear. I could feel every hair my hand was touching. I felt so relaxed and at ease. I know that under the appropriate circumstances, this material would lead to uninhibited eroticism.”

    โ€” Alexander Shulgin, PiHKAL (with 30 mg)

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