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    Racemorphan molecular structure

    Racemorphan Stats & Data

    Depressant Opioid
    PubChem CID 3918
    NPS DataHub
    MW257.38
    FormulaC17H23NO
    CAS297-90-5
    IUPAC17-methyl-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-trien-4-ol
    SMILESOc1ccc2CC3N(C)CCC4(CCCCC34)c2c1
    InChIKeyJAQUASYNZVUNQP-UHFFFAOYSA-N
    Chemical Class medicine
    Psychoactive Class Depressant

    Pharmacology

    DrugBank

    Metabolism

    Levorphanol is extensively metabolized in the liver and is eliminated as the glucuronide metabolite. Half Life: 11-16 hours

    Toxicity

    PubChem

    Like other mu-agonist opioids it is believed to act at receptors in the periventricular and periaqueductal gray matter in both the brain and spinal cord to alter the transmission and perception of pain.

    LD50

    • LD50: 150 mg/kg (Oral, Rat) (A308)

    Carcinogenicity

    No indication of carcinogenicity to humans (not listed by IARC).

    Health effects (PubChem excerpts)

    Medical problems can include congested lungs, liver disease, tetanus, infection of the heart valves, skin abscesses, anemia and pneumonia. Death can occur from overdose.

    Effect Profile

    Curated
    Opioid 5.1

    Strong euphoria with moderate itching/nausea, mild sedation

    Euphoria / Warmth×3
    9
    Analgesia×2
    0
    Sedation / Relaxation×1
    5
    Itching / Nausea×1
    6
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Racemorphan

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~35d
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