Rasagiline
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- duration data present
- dose data not in PW/TripSit (unverifiable)
- 1 source
- duration data present
- dose data not in PW/TripSit (unverifiable)
Aliases: Azilect, Tvp-1012, Agn-1135
Summary
Rasagiline irreversibly acylates the flavin site of MAO-B, giving approximately 90% inhibition at 1 mg/day within 1-2 weeks. Although its plasma half-life is approximately 3 h, functional recovery depends on MAO-B resynthesis (approximately 40 days), so a single 1 mg dose can keep tyramine thresholds lower for several days. Selectivity diminishes above 2 mg/day, raising dietary and pressor risk comparable to classical non-selective MAOIs.
Dose Information
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset |
|---|---|---|---|
| Oral (Tablet; Sublingually Dissolved) | 30-60 min | 1-2 hrs | 12-24 hrs |
| Oral (Powder / Capsule) | 30-60 min | 1-2 hrs | 12-24 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Mild stimulation with low anxiety/jitters
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Reduced fatigue
- Stimulation
- Slight appetite suppression
- Occasional insomnia
- Increased heart rate
- Subtle mental alertness
- Enhanced motivation
- Mild euphoria
- Vivid dreams
- Alertness enhancement
- Talkativeness
- Light sensitivity
Pill Identifiers
Helpful Links
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