Salvinorin A - Substance Search

Summary PsychonautWiki

Salvinorin A is the main active psychoactive molecule within Salvia Divinorum, a Mexican plant which has a long history of use as an entheogen by indigenous Mazatec shamans. It is structurally distinct from other naturally occurring hallucinogens (such as DMT, psilocin and mescaline) because it contains no nitrogen atoms, making it a terpenoid and not an alkaloid as is the norm. This means it cannot be rendered as a salt.

Dose Information PsychonautWiki Erowid

ROA	Light	Common	Strong	Heavy
Smoked	200-500µg	500-1000µg	1000-1500µg	1500µg+

Light Common Strong Heavy

Effect Profile

3 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Psychedelic 6.5

Strong 6/10

Strong visuals with moderate headspace, mild auditory effects and body load

Visual Intensity ×3

8

color enhancement drifting tracers pattern recognition enhancement visual distortions

Headspace Depth ×3

6

conceptual thinking introspection time distortion confusion

Auditory Effects ×1

4

auditory distortion

⚠ Body Load / Somatic Effects ×1

4

nausea increased heart rate

Based on reports from:

Erowid Experience Reports PsychonautWiki Salvinorin A

Add missing routes to PsychonautWiki Journal

The PsychonautWiki Journal app already has Salvinorin A, but its built-in entry only covers Smoked, Sublingual. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

⬇ Download import file Import this file as custom substances and you get "Salvinorin A (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.

Custom Unit doses

Smokedcommon ~ 750 µg

Dose & duration (reference)

Salvinorin A: routes the PsychonautWiki Journal app is missing
Source: SubstanceSearch (substancesearch.com)

Smoked dose (µg): threshold 200 · light 200-500 · common 500-1000 · strong 1000-1500 · heavy 1500+

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.

Tolerance

Build-up develops rapidly after a single use

Reset 7–14 days for baseline

Tolerance Decay

Half tolerance 7d Baseline ~14d

Formal human tolerance data are lacking. Summaries and user reports suggest minimal acute tolerance; some anecdotal ‘reverse tolerance’/sensitization claims exist but are unverified. Avoid escalating doses rapidly; if reattempting, wait at least a day and reassess mindset and setting.

Effects Erowid

Aggregated from 3 Erowid experience reports

Positive Effects 0

Adverse Effects 1

Anxiety 100.0% 70%

Combinations

Cross-Check Salvinorin A with another substance

Community Trip Reports

Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

Erowid 2 reports 1 positive 1 neutral visit

Salvinorin A Journeys positive exp #77010

Citation: Gwyllm. 'Salvinorin A Journeys'. The Entheogen Review . Winter Solstice 1998;7(4):90-2. ~1.00-1.25 mg salvinorin A. Ingested with tin foil/straw/lighter method. Immediate and strong effects. Mouth quickly dries, I have never had this experience with salvinorin A before.

I Smoked a High Dose in an MRI Machine neutral exp #118585

Smoking Salvia in an MRI Machine This is my experience report of when I smoked a high dose of FDA approved, pure Salvinorin-A, as a research participant in a Salvia study at Johns Hopkins University.

Salvinorin A's nerd page Pharmacology, chemical data, effect profiles, and more

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Helpful Links

📘 Experience Reports 📖 PsychonautWiki 📖 Erowid

Report an issue or suggest an edit

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Salvinorin A Well-documented Well-documented Multiple authoritative sources agree on dosing and effects. 2 corroborating sources 1 ROA with full dose ladder duration data present 19 combo interactions documented toxicity data (PsychonautWiki, PubChem)