It's past bedtime, and I'm tired, or should be tired. Just finished an essay, now About to sleep. Been a little wired all night. But it's 1 AM, and I need sleep. 25 mg DPH. Little pink pill fragments, bitter taste, an a mouthful of cold water. Lie down to sleep with slightly numb lips. Plus 6 mg melatonin.
Serotonin
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- no dose data
- 19 combo interactions documented
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- no dose data
- 19 combo interactions documented
Summary
Serotonin (also known as 5-hydroxytryptamine, or 5-HT), is a naturally occuring chemical found in humans, animals, and plants alike.
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
5.8
Strong
6/10
Strong visuals with mild headspace, auditory effects, and body load
Visual Intensity
×3
8
color enhancement
drifting
tracers
pattern recognition enhancement
visual distortions
Headspace Depth
×3
4
introspection
time distortion
confusion
Auditory Effects
×1
4
auditory distortion
Body Load / Somatic Effects
×1
4
nausea
increased heart rate
Based on reports from:
Tolerance
Build-up
develops rapidly after a single use
Reset
7–14 days for baseline
Tolerance Decay
Full tolerance
1h
Half tolerance
10d
Baseline
~14d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Positive
- Stimulation
- Mental/physical stimulation
Negative
- Nausea
- Pupil dilation
- Increased heart rate
- Insomnia
- Restlessness
- Dilated pupils
- Decreased appetite
- Sedation
Positive
- Introspection
- Euphoria
- Wakefulness
- Empathy
- Analysis enhancement
- Insight
Negative
- Anxiety
- Confusion
- Time distortion
- Ego softening
Positive
- Color enhancement
- Increased music appreciation
- Tracers
- Tactile enhancement
- Enhanced tactile sensation
- Pattern recognition enhancement
Negative
- Appetite suppression
- Visual distortions
- Drifting
- Auditory distortion
Combinations
Cross-Check Serotonin with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Bluelight 2 threads 1 neutral 1 cautionary visit
I posted something about this in the Health Q&A the other day and someone suggested I write down the details in a trip report, as a warning to others as much as anything else.
Serotonin's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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