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    Disclaimer
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    ⚠ Opioids carry significant risk of respiratory depression, physical dependence, and fatal overdose. Never combine with other depressants.

    Spirochlorphine Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • duration data present
    • 19 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Aliases: Spc, R-6890

    Summary dose.wiki

    Marketed only as a research chemical with potency reported as 2-5 times that of fentanyl. Reported solubility approximately 3 mg/mL in 10% ethanol/PG solution. Users stress volumetric dosing and allergy testing because a 10-fold error spans the entire active range.

    Dose Information dose.wiki

    Dose basis. The dose figures on this page are not clinical data. They are aggregated from community reports by a secondary source whose own notes state there is no human pharmacokinetic study behind them, and our internal audit flags this substance's dosing as unverifiable. Treat them as a rough orientation, not a safe range. This is a microgram-active opioid: a normal milligram scale cannot weigh a dose of it accurately, and a weighing error here is measured in lethal multiples rather than percentages. Volumetric dosing is the only defensible method, and batch-to-batch potency in the unregulated supply varies enormously. Assume full respiratory depression, keep naloxone to hand, never dose alone, and never combine with benzodiazepines, alcohol or other depressants.

    ROA Threshold
    Insufflated 50-100ug
    Intravenous 0.2mg

    Only a threshold dose is documented for this substance β€” the smallest amount with a noticeable effect. There is no published light/common/strong ladder to show above it.

    Onset, Duration & After-effects dose.wiki

    ROA Onset Peak Offset After Effects Total
    Insufflated 5-15 min 30-90 min 2-4 hrs 2-6 hrs 2.58-5.75 hrs
    Intravenous 1-5 min 30-90 min 2-4 hrs 2-6 hrs 2.52-5.58 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 7.9
    Intense 8/10

    Strong euphoria and pain relief with moderate itching/nausea, mild sedation

    Euphoria / Warmth ×3
    10
    physical euphoria cognitive euphoria euphoria warmth
    Analgesia ×2
    8
    pain relief analgesia
    Sedation / Relaxation ×1
    5
    sedation muscle relaxation
    Itching / Nausea ×1
    6
    nausea constipation

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Spirochlorphine there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    Name
    Spirochlorphine
    Unit
    Β΅g
    Description
    Spirochlorphine
    Source: SubstanceSearch (substancesearch.com)
    
    Insufflated dose (Β΅g): threshold 50-100ug
    Intravenous dose (mg): threshold 0.2
    
    Insufflated duration: onset 5-15m Β· peak 0.5-1.5h Β· offset 2-4h Β· total 2.58-5.75h Β· after-effects 2-6h
    Intravenous duration: onset 1-5m Β· peak 0.5-1.5h Β· offset 2-4h Β· total 2.52-5.58h Β· after-effects 2-6h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks β€” tolerance loss greatly increases overdose risk

    Tolerance Decay

    Full tolerance 3d Half tolerance 10d Baseline ~28d

    Opioid tolerance builds quickly and decays slowly; precise rates for SPC are unknown. Cross‑tolerance with other μ‑opioids is expected by pharmacological class inference, but magnitudes are uncertain. Data quality low/anecdotal.

    Effects dose.wiki

    Positive
    • Physical euphoria
    • Pain relief
    • Stimulation
    • Analgesia
    • Muscle relaxation
    Negative
    • Respiratory depression
    • Nausea
    Neutral
    • Sedation
    • Itchiness
    • Pupil constriction
    Positive
    • Cognitive euphoria
    • Anxiety suppression
    • Reduced anxiety
    • Wakefulness
    • Motivation enhancement
    • Euphoria
    Negative
    • Compulsive redosing
    • Constipation
    • Motivation suppression
    • Anxiety
    Positive
    • Warmth
    • Increased music appreciation
    • Increased libido
    Negative
    • Appetite suppression
    • Light sensitivity
    • Disinhibition
    • Dehydration
    Neutral
    • Dulled perception
    • Internal hallucination
    • Warm flush

    Combinations

    Cross-Check Spirochlorphine with another substance

    Helpful Links