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    Disclaimer
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    ⚠ Opioids carry significant risk of respiratory depression, physical dependence, and fatal overdose. Never combine with other depressants.

    Spirochlorphine Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 1 source
    • 2 ROAs with full dose ladders
    • duration data present
    • 19 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Aliases: Spc, R-6890

    Depressant Research-chemical Opioid

    Summary TheDrug.Wiki

    Marketed only as a research chemical with potency reported as 2-5 times that of fentanyl. Reported solubility approximately 3 mg/mL in 10% ethanol/PG solution. Users stress volumetric dosing and allergy testing because a 10-fold error spans the entire active range.

    Dose Information TheDrug.Wiki

    ROA Light Common Strong Heavy
    Insufflated 100-250Β΅g 250-400Β΅g 400-800Β΅g 800Β΅g+
    Intravenous 0.2-0.5mg 0.5-1mg 1-2mg 2mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Peak Offset After Effects Total
    Insufflated 5-15 min 30-90 min 2-4 hrs 2-6 hrs 4-8 hrs
    Intravenous - 30-90 min 2-4 hrs 2-6 hrs 4-8 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 7.9
    Intense 8/10

    Strong euphoria and pain relief with moderate itching/nausea, mild sedation

    Euphoria / Warmth ×3
    10
    physical euphoria cognitive euphoria euphoria warmth
    Analgesia ×2
    8
    pain relief analgesia
    Sedation / Relaxation ×1
    5
    sedation muscle relaxation
    ⚠ Itching / Nausea ×1
    6
    nausea constipation
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Spirochlorphine
    View methodology →

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks β€” tolerance loss greatly increases overdose risk

    Tolerance Decay

    Full tolerance 3d Half tolerance 10d Baseline ~28d

    Opioid tolerance builds quickly and decays slowly; precise rates for SPC are unknown. Cross‑tolerance with other μ‑opioids is expected by pharmacological class inference, but magnitudes are uncertain. Data quality low/anecdotal.

    Cross-Tolerances

    fentanyl analogues
    70%
    benzimidazole opioids (e.g., isotonitazene class)
    60%

    Effects TheDrug.Wiki

    Positive
    • Physical euphoria
    • Pain relief
    • Stimulation
    • Analgesia
    • Muscle relaxation
    Negative
    • Respiratory depression
    • Nausea
    Neutral
    • Sedation
    • Itchiness
    • Pupil constriction
    Positive
    • Cognitive euphoria
    • Anxiety suppression
    • Reduced anxiety
    • Wakefulness
    • Motivation enhancement
    • Euphoria
    Negative
    • Compulsive redosing
    • Constipation
    • Motivation suppression
    • Anxiety
    Positive
    • Warmth
    • Increased music appreciation
    • Increased libido
    Negative
    • Appetite suppression
    • Light sensitivity
    • Disinhibition
    • Dehydration
    Neutral
    • Dulled perception
    • Internal hallucination
    • Warm flush

    Combinations TripSit

    Cross-Check Spirochlorphine with another substance

    Spirochlorphine's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    πŸ“˜ Experience Reports πŸ“– TheDrug.Wiki πŸ“– PsychonautWiki