SR-14968
Summary
Sold exclusively as a research chemical with no clinical trials in humans. Despite biased agonist properties in vitro, behaves more like a traditional opioid in vivo with respiratory depression at higher doses. Anecdotal reports describe slow onset (1-3 hours to peak), long duration (effects persisting 12-24 hours), and high potency.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 30-90 min | 1-2 hrs | 3-6 hrs | 4-8 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Opioid
6.3
Strong
6/10
Strong euphoria with moderate itching/nausea, mild sedation and pain relief
Euphoria / Warmth
×3
9
physical euphoria
cognitive euphoria
euphoria
Analgesia
×2
4
pain relief
Sedation / Relaxation
×1
5
sedation
muscle relaxation
Itching / Nausea
×1
6
nausea
constipation
Based on reports from:
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7โ14 days for partial reset; full reset may take weeks โ tolerance loss greatly increases overdose risk
Cross-Tolerances
Effects
Positive
- Pain relief
- Physical euphoria
- Muscle relaxation
- Stimulation
Negative
- Respiratory depression
- Nausea
- Pupil dilation
- Sedation
- Itchiness
- Pupil constriction
Positive
- Cognitive euphoria
- Reduced anxiety
- Wakefulness
- Focus enhancement
- Motivation enhancement
- Euphoria
Negative
- Constipation
- Compulsive redosing
- Anxiety
- Cognitive fatigue
Positive
- Tactile enhancement
- Color enhancement
- Increased music appreciation
Negative
- Appetite suppression
- Light sensitivity
- Disinhibition
- Dulled perception
- Increased sexuality
- Visual and auditory hallucinations
- Drifting
Combinations
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