STS-135
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 16 combo interactions documented
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 16 combo interactions documented
Summary
STS-135 (also called N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide or 5F-APICA) is a drug that acts as a potent agonist for the cannabinoid receptors which produces subjective effects somewhat similar to that of cannabis with a short duration and an emphasis on intense physical sensations. There is very little information regarding the pharmacology of this compound within the scientific literature. Despite this, however, it is available for sale as a grey area research chemical through online vendors.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Smoked | 0.5-1.5mg | 1.5-2mg | 2-4mg | 4mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Smoked | - | 12-48 min | 12-30 min | 6-12 min | 30-60 min |
Import into PsychonautWiki Journal
The PsychonautWiki Journal app includes STS-135, but its built-in data can be thinner than ours. Importing this file adds a separate "STS-135 (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.
Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Pain relief
- Stimulation
- Dry mouth
- Tachycardia
- Nausea/vomiting
- Strong dysphoria on comedown
- Nausea
- Red eyes
- Spontaneous bodily sensations
- Vasodilation
- Thought connectivity
- Mindfulness
- Conceptual thinking
- Euphoria
- Anxiety
- Paranoia
- Rapid, intense intoxication
- Anxiolysis or severe anxiety/panic
- Time distortion
- Dissociation at high doses
- Increased music appreciation
- Auditory acuity enhancement
- Dehydration
- Visual sharpening or mild pseudo-hallucinations
- Dulled perception
- Auditory distortion
- Changes in felt gravity
- Perception of bodily heaviness
- Appetite intensification
- Drifting
Combinations
Cross-Check STS-135 with another substanceHelpful Links
Report an issue or suggest an edit
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