Tetrahydrocannabutol
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- no dose data
- 27 combo interactions documented
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- no dose data
- 27 combo interactions documented
Summary
Tetrahydrocannabutol (THCB) is the butyl homologue of THC — the same dibenzopyran scaffold with a four-carbon side chain in place of THC's five. It occurs naturally in cannabis in trace amounts and binds CB1 with affinity comparable to THC in the limited published assays. Human data is essentially nonexistent; products sold as THCB are semi-synthetic hemp derivatives of untested purity.
Tolerance
Build-up
develops over weeks of regular use via CB1 receptor downregulation
Reset
2–4 weeks for most users; heavy users may need longer
Tolerance Decay
Full tolerance
3d
Half tolerance
21d
Baseline
~28d
Effects
Effect glossary — · full glossary
Positive
Negative
Positive
Negative
Positive
Negative
Combinations
Cross-Check Tetrahydrocannabutol with another substanceHelpful Links
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