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    Tetrahydrocannabutol Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data
    • 16 combo interactions documented

    Summary PsychonautWiki

    Tetrahydrocannabutol (THCB) is the butyl homologue of THC — the same dibenzopyran scaffold with a four-carbon side chain in place of THC's five. It occurs naturally in cannabis in trace amounts and binds CB1 with affinity comparable to THC in the limited published assays. Human data is essentially nonexistent; products sold as THCB are semi-synthetic hemp derivatives of untested purity.

    Tolerance

    Build-up develops over weeks of regular use via CB1 receptor downregulation
    Reset 2–4 weeks for most users; heavy users may need longer

    Tolerance Decay

    Full tolerance 3d Half tolerance 21d Baseline ~28d

    Effects

    Positive
    • Pain relief
    • Anxiolysis
    Negative
    • Nausea
    • Dry mouth
    • Increased heart rate
    • Tachycardia
    • Nausea/vomiting
    Neutral
    • Sedation
    • Spontaneous bodily sensations
    • Vasodilation
    Positive
    • Euphoria
    • Anxiety suppression
    • Thought connectivity
    • Reduced anxiety
    Negative
    • Anxiety
    • Paranoia
    • Motor control loss
    • Short-term memory suppression
    • Psychosis
    Neutral
    • Time distortion
    Positive
    • Color enhancement
    • Increased music appreciation
    • Appetite enhancement
    • Auditory acuity enhancement
    Negative
    • Dehydration
    Neutral
    • Dulled perception
    • Visual distortions
    • Appetite intensification
    • Changes in felt gravity
    • Perception of bodily heaviness

    Combinations

    Cross-Check Tetrahydrocannabutol with another substance

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