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    Disclaimer
    โ˜  This is a fentanyl analogue active in microgram doses. Accidental overdose can be rapidly fatal. Naloxone should always be on hand.
    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Tetrahydrofuran-Fentanyl

    Aliases: Thf-f, thff

    Summary TripSit

    An analogue of fentanyl that is unknown in literature. Is most likely less potent than most other analogues. Yet very few reports are around.

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 5.4
    Moderate+ 5/10

    Strong euphoria with mild sedation and itching/nausea

    Euphoria / Warmth ×3
    9
    physical euphoria cognitive euphoria euphoria
    Analgesia ×2
    0
    Sedation / Relaxation ×1
    5
    sedation muscle relaxation
    Itching / Nausea ×1
    4
    nausea

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7โ€“14 days for partial reset; full reset may take weeks โ€” tolerance loss greatly increases overdose risk

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~35d

    Effects

    Positive
    • Stimulation
    • Physical euphoria
    • Muscle relaxation
    Negative
    • Motor impairment
    • Increased heart rate
    • Nausea
    • Vasoconstriction
    • Respiratory depression
    • Teeth grinding
    Neutral
    • Sedation
    Positive
    • Reduced anxiety
    • Cognitive euphoria
    • Euphoria
    • Anxiety suppression
    • Wakefulness
    Negative
    • Anxiety
    • Compulsive redosing
    • Dizziness
    • Thought deceleration
    Neutral
    • Time distortion
    Positive
    • Increased music appreciation
    • Increased libido
    • Tactile enhancement
    • Color enhancement
    Negative
    • Disinhibition
    • Appetite suppression
    • Dehydration
    • Light sensitivity
    • Double vision
    Neutral
    • Dulled perception

    Combinations TripSit

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