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    THC-O-acetate

    Summary PsychonautWiki

    THC-O-acetate Legal status UK: Class B US: Unscheduled Identifiers IUPAC name (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-yl acetate CAS Number 23132-17-4 ☒ PubChem CID 198013 ChemSpider 171383 check UNII VHV54M2AES CompTox Dashboard (EPA) DTXSID30177698 Edit this at Wikidata Chemical and physical data Formula C23H32O3 Molar mass 356.506 g·mol−1 SMILES O=C(Oc2cc(cc1OC([C@@H]3CC/C(=C\[C@H]3c12)C)(C)C)CCCCC)C InChI InChI=1S/C23H32O3/c1-6-7-8-9-17-13-20(25-16(3)24)22-18-12-15(2)10-11-19(18)23(4,5)26-21(22)14-17/h12-14,18-19H,6-11H2,1-5H3/t18-,19-/m1/s1 check Key:DEWSJDIJFWQLOA-RTBURBONSA-N check THC acetate ester (THC-O-acetate, THC acetate, O-acetyl-Δ9-THC, THC-O, ATHC) is the acetate ester of THC. Physical data, chemistry & properties O-acetyl-Δ8-THC [1] O-acetyl-Δ8-THC [1] THC acetate ester can be synthesized from THC,[1][2] or from THCA. The acetylation of THC does not change the properties of the compound to the same extent as with other acetate esters, as the parent compound (THC) is already highly lipophilic, but potency is nonetheless increased to some extent.

    Tolerance

    Build-up develops over weeks of regular use via CB1 receptor downregulation
    Reset 2–4 weeks for most users; heavy users may need longer

    Tolerance Decay

    Full tolerance 3d Half tolerance 21d Baseline ~28d

    Effects

    Positive
    • Pain relief
    • Anxiolysis
    Negative
    • Nausea
    • Dry mouth
    • Increased heart rate
    • Tachycardia
    • Nausea/vomiting
    Neutral
    • Sedation
    • Spontaneous bodily sensations
    • Vasodilation
    Positive
    • Euphoria
    • Anxiety suppression
    • Thought connectivity
    • Reduced anxiety
    Negative
    • Anxiety
    • Paranoia
    • Motor control loss
    • Short-term memory suppression
    • Psychosis
    Neutral
    • Time distortion
    Positive
    • Color enhancement
    • Increased music appreciation
    • Appetite enhancement
    • Auditory acuity enhancement
    Negative
    • Dehydration
    Neutral
    • Dulled perception
    • Visual distortions
    • Appetite intensification
    • Changes in felt gravity
    • Perception of bodily heaviness

    Combinations TripSit

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