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    Tiagabine Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data
    • PubChem toxicity data

    Aliases: Gabitril

    Summary Erowid

    Tiagabine is an anticonvulsant prescribed as an add-on drug to help control epileptic seizures. It is believed to work by enhancing the inhibitory neurotransmitter GABA. It is also prescribed off-label in the treatment of bi-polar disorder [BPD], chronic anxiety disorder, and insomnia.

    Tolerance

    Build-up varies by mechanism; therapeutic tolerance may develop over weeks of regular use
    Reset typically days to weeks after discontinuation

    Tolerance Decay

    Full tolerance 3d Half tolerance 8d Baseline ~14d

    Effects Erowid

    Aggregated from 7 Erowid experience reports

    Positive Effects 1

    Sedation 57.1% 70%

    Adverse Effects 0

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 6 reports 1 positive 3 neutral 2 cautionary visit
    Not Fun positive exp #31573

    I was prescribed Gabitril for my anxiety. My prescription is to take up to three 4mg pills at bedtime. Well, I was bored last night and decided to take nine 4mg pills, for a total of 36mg. Let me tell you, this is not something you want to try to trip on. It's not fun.

    Twilex · Tiagabine (Gabitril) · 36 mg oral
    Too Intense for Comfort neutral exp #29090

    Last weekend I was bored so I decided to pay my good friend 'G' a visit. Upon arriving at his house he told me he had gotten a new perscription to Gabitril, something I had never previously heard of.

    Gabitril · Tiagabine (Gabitril) · 24 mg oral
    Black Outs and Refrigerators neutral exp #38619

    [Erowid Note: The dose described in this report is very high, potentially beyond Erowid's 'heavy' range, and could pose serious health risks or result in unwanted, extreme effects.

    Adam · Tiagabine (Gabitril) · 72 mg oral
    Gifts from the Pain Doctor neutral exp #39592

    My chronic pain doctor gave to me several boxes of free samples of a drug called Gabitril. Apparently, it is good against nerve related pain (pinched nerves in the spine, etc) so I said I would give it a shot. She warned me it might pack a punch though, dizziness, drowsiness, the works.

    Anonymous · Tiagabine (Gabitril) · 4.0 mg oral
    An Odd Night cautionary exp #36006

    About three weeks ago, I was hanging out with my new roommate (we’ve been friends for a long time), and I was feeling too sober yet didn’t have any money for trees or alcohol, and he is prescribed many things for bipolar disorder, anxiety, depression and also adhd.

    Thrillhouse22 · Tiagabine (Gabitril) · 48 mg oral
    Totally Brain Dead cautionary exp #39040

    This happened to me not too long ago. Since I saw there weren't any reports on Tiagabine and it's dangers, I decided to submit this. Please be forewarned that this drug is not something you should even consider messing with.

    Planeteer · Tiagabine (Gabitril) · 60 mg oral

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