Summary
Tiagabine is an anticonvulsant prescribed as an add-on drug to help control epileptic seizures. It is believed to work by enhancing the inhibitory neurotransmitter GABA. It is also prescribed off-label in the treatment of bi-polar disorder [BPD], chronic anxiety disorder, and insomnia.
Tolerance
Build-up
varies by mechanism; therapeutic tolerance may develop over weeks of regular use
Reset
typically days to weeks after discontinuation
Effects
Positive
- Physical euphoria
- Muscle relaxation
- Anxiolytic
Negative
- Motor impairment
- Nausea
- Respiratory depression
- Sedation
- Sedative
- Dystaxia
- Itchiness
Positive
- Reduced anxiety
- Anxiety suppression
- Cognitive euphoria
- Euphoria
Negative
- Dizziness
- Compulsive redosing
- Thought deceleration
- Amnesia
- Motor control loss
- Constipation
Positive
- Increased music appreciation
- Increased libido
Negative
- Disinhibition
- Appetite suppression
- Dehydration
- Light sensitivity
- Double vision
- Acuity suppression
- Dulled perception
- Internal hallucinations