Tolibut
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- no dose data
- classified Tentative
- classified Research-chemical
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- no dose data
- classified Tentative
- classified Research-chemical
Summary
Analogue of GABA, and the 4-methyl analogue of Phenibut. Has similar effects, acts on GABA(B).
Tolerance
Build-up
develops over 1–4 weeks of regular use
Reset
days to weeks depending on duration of use
Tolerance Decay
Full tolerance
3d
Half tolerance
8d
Baseline
~14d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Positive
- Stimulation
Negative
- Motor impairment
- Increased heart rate
- Pupil dilation
- Nausea
- Insomnia
- Vasoconstriction
- Restlessness
- Sedation
- Decreased appetite
Positive
- Reduced anxiety
- Euphoria
- Cognitive euphoria
- Wakefulness
- Empathy
Negative
- Anxiety
- Confusion
- Compulsive redosing
- Time distortion
- Talkativeness
Positive
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Brightened colour
Negative
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Dulled perception
- Drifting
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