U-51754
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Tentative
- classified Research-chemical
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: Methene-u-47700, methene-u47700
Summary
A very potent opioid, that seems to have a fair bit of ฮบ-opioid action. So Dyshopria, Auditory hallucinations can be an effect. Is an analogue of U-47700.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Rectal | 1-3mg | 3-5mg | 5-10mg | 10mg+ |
Onset, Duration & After-effects
| ROA | Onset | Total |
|---|---|---|
| Rectal | 5-10 min | 1-2 hrs |
Effect Profile
class estimateScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- No reports exist for this substance. Its effect list is the one shared by 2 other substances of the same class, so the scores below describe the class, not this compound.
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate euphoria with mild itching/nausea, low sedation
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The PsychonautWiki Journal logging app doesn't include every substance. To track U-51754 there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
U-51754 Source: SubstanceSearch (substancesearch.com) Rectal dose (mg): light 1-3 ยท common 3-5 ยท strong 5-10 ยท heavy 10+ Rectal duration: onset 5-10m ยท total 1-2h ยท after-effects 3-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 4 mg (Rectal).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session โ the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Motor impairment
- Increased heart rate
- Nausea
- Insomnia
- Vasoconstriction
- Restlessness
- Sedation
- Decreased appetite
- Reduced anxiety
- Euphoria
- Cognitive euphoria
- Wakefulness
- Empathy
- Anxiety
- Confusion
- Compulsive redosing
- Time distortion
- Talkativeness
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Brightened colour
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Dulled perception
- Drifting
Combinations
Cross-Check U-51754 with another substanceHelpful Links
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