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    Venlafaxine

    Aliases: Efexor, Effexor, Effexor xr

    Summary Erowid

    Venlafaxine is a serotonin and norepinephrine reuptake inhibitor which is used in the treatment of depression and general anxiety disorder. It is also used off-label to treat a variety of other disorders.

    Tolerance

    Build-up varies by mechanism; therapeutic tolerance may develop over weeks of regular use
    Reset typically days to weeks after discontinuation

    Tolerance Decay

    Full tolerance 3d Half tolerance 8d Baseline ~14d

    Effects Erowid

    Aggregated from 155 Erowid experience reports

    Positive Effects 8

    Stimulation 36.8% 70%
    Euphoria 17.4% 70%
    Empathy 16.1% 70%
    Focus Enhancement 16.1% 70%
    Music Enhancement 12.9% 70%
    Color Enhancement 10.3% 70%
    Tactile Enhancement 7.7% 70%
    Body High 3.9% 70%

    Adverse Effects 14

    Anxiety 55.5% 70%
    Confusion 27.1% 70%
    Nausea 22.6% 70%
    Increased Heart Rate 9.7% 70%
    Pupil Dilation 9.0% 70%
    Sweating 8.4% 70%
    Seizure 8.4% 70%
    Muscle Tension 6.5% 70%
    Appetite Suppression 5.2% 70%
    Jaw Clenching 5.2% 70%
    Psychosis 5.2% 70%
    Memory Suppression 4.5% 70%
    Headache 3.2% 70%
    Motor Impairment 2.6% 70%

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