Zolazepam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 3 ROAs with full dose ladders
- duration data present
- 17 combo interactions documented
- 1 source
- 3 ROAs with full dose ladders
- duration data present
- 17 combo interactions documented
Summary
A substance that is structurally related to benzodiazepines. Is only used in Veterinary medicine. It is usually used in tandem with either the potent NMDA antagonist Tiletamine (at a 1:1 ratio) or with the α2 adrenergic receptor agonist Xylazine.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | 1-3mg | 3-6mg | 6-12mg | 12mg+ |
| Intramuscular | 1-3mg | 3-5mg | 5-10mg | 10mg+ |
| Oral | 2.5-5mg | 5-10mg | 10-20mg | 20mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak |
|---|---|---|
| Insufflated | 5-10 min | 2-3 hrs |
| Intramuscular | 1-5 min | 2-4 hrs |
| Oral | 10-30 min | 4-6 hrs |
Effect Profile
3 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria and anxiolysis with mild sedation, low cognitive impairment
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Physical euphoria
- Muscle relaxation
- Motor impairment
- Increased heart rate
- Nausea
- Vasoconstriction
- Respiratory depression
- Teeth grinding
- Sedation
- Reduced anxiety
- Cognitive euphoria
- Euphoria
- Anxiety suppression
- Wakefulness
- Anxiety
- Compulsive redosing
- Dizziness
- Thought deceleration
- Time distortion
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Color enhancement
- Disinhibition
- Appetite suppression
- Dehydration
- Light sensitivity
- Double vision
- Dulled perception
Combinations
Cross-Check Zolazepam with another substanceHelpful Links
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