1B-LSD
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 19 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 19 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Aliases: 1b, 1-butyryl-lsd
Summary
1B-LSD is an N1-acylated prodrug that is rapidly hydrolyzed in vitro and in vivo to LSD via CYP1A2 and CYP3A4 enzymes. Animal studies show approximately 14% the potency of LSD by weight; blotters marketed at 100 ug 1B-LSD produce subjective effects comparable to 75-100 ug LSD in many users. Because it is a prodrug, CYP1A2/3A4 inhibitors or inducers could alter intensity and onset.
Perspectives
“The overall attributes of the trip I would describe as lucidity, with light overall visuals mostly built of alterations, but with an underlying cognitive intensity and depth that makes for a truly profound, though not necessarily intense, experience.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 25-75µg | 75-150µg | 150-300µg | 300µg+ |
| Sublingual | 25-75µg | 75-150µg | 150-300µg | 300µg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 19-60 min | 0.75-2 hrs | 3-5 hrs | 3-5 hrs | 8-12 hrs |
| Sublingual | 19-60 min | 0.75-2 hrs | 3-5 hrs | 3-5 hrs | 8-12 hrs |
Effect Profile
2 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong visuals, headspace, and auditory effects with moderate body load
Add missing routes to PsychonautWiki Journal
The PsychonautWiki Journal app already has 1B-LSD, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.
- Sublingualcommon ~ 112.5 µg
1B-LSD: routes the PsychonautWiki Journal app is missing Source: SubstanceSearch (substancesearch.com) Sublingual dose (µg): threshold 15-25ug · light 25-75 · common 75-150 · strong 150-300 · heavy 300+ Sublingual duration: onset 0.32-1h · come-up 0.75-2h · peak 3-5h · offset 3-5h · total 8-12h · after-effects 6-24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Rapid tolerance after a single session; meaningful reduction after ~5–7 days; near‑baseline by ~14 days is typical for LSD‑like psychedelics. Data are based on human experience and general psychedelic pharmacology rather than controlled trials.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Stamina enhancement
- Creativity enhancement
- Pupil dilation
- Nausea
- Vasoconstriction
- Increased heart rate
- Increased blood pressure
- Increased perspiration
- Seizure
- Muscle twitching
- Spontaneous bodily sensations
- Difficulty urinating
- Excessive yawning
- Muscle contractions
- Increased salivation
- Stamina intensification
- Analysis enhancement
- Conceptual thinking
- Emotion enhancement
- Personal meaning enhancement
- Cognitive euphoria
- Laughter fits
- Wakefulness
- Novelty enhancement
- Unity and interconnectedness
- Increased sense of humor
- Immersion intensification
- Anxiety
- Delusion
- Paranoia
- Thought disorganization
- Memory suppression
- Time distortion
- Thought acceleration
- Ego dissolution
- Machinescapes
- Depth perception distortions
- Recursion
- Perspective distortion
- Multiple thought streams
- Personality regression
- Thought loop
- Personal bias suppression
- Existential self-realization
- Ego replacement
- Emotion intensification
- Focus intensification
- Personal meaning intensification
- Suggestibility intensification
- Spirituality intensification
- Tactile enhancement
- Colour enhancement
- Visual acuity enhancement
- Pattern recognition enhancement
- Tracers
- Increased music appreciation
- Synaesthesia
- Increased libido
- Bodily control enhancement
- Color enhancement
- Color shifting
- Auditory acuity enhancement
- Appetite suppression
- Visual drifting
- After images
- Symmetrical texture repetition
- Internal hallucination
- Auditory hallucination
- Auditory distortion
- Scenery slicing
- External hallucination
- Autonomous entity
- Drifting
- Color tinting
- Perspective hallucination
- Tactile intensification
Combinations
Cross-Check 1B-LSD with another substanceTrip Reports
Bluelight Reference Guide
Lysergamides The Small & Handy 1-Bu-LSD (1B-LSD) Thread
Apparently vendors are sending out samples for testing right now. Its supposed to be similar to ALD-52 and 1P-LSD. The exact chemical structure isnt out yet but it should be pretty easy to guess. Is it even active ? I have a feeling its not but Id love for someone with more knowledge to correct me
Read full thread on Bluelight →Helpful Links
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