Summary
1cP-MiPLA (1-cyclopropionyl-N-methyl-N-isopropyllysergamide) is a novel lysergamide first appearing on research chemical markets around 2020. It acts as a prodrug that rapidly hydrolyzes to MiPLA, similar to how 1P-LSD converts to LSD. Potency is approximately 60-80% of LSD by weight; many users find 150 ug comparable to 100 ug LSD. The experience is notably shorter (4-6 hours vs 8-12 hours for LSD) and described as more recreational with less headspace intensity. Visual effects are clean and cartoonish, while the body high is pleasurable without the anxiety common at higher LSD doses.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 100-150µg | 150-200µg | 200-250µg | 300µg+ |
| Sublingual | 100-150µg | 150-200µg | 200-250µg | 300µg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 20-40 min | 45-90 min | 1-2 hrs | 1-2 hrs | 2-6 hrs |
| Sublingual | 20-40 min | 45-90 min | 1-2 hrs | 1-2 hrs | 2-6 hrs |
Tolerance
Build-up
develops rapidly after a single use (lysergamide)
Reset
7–14 days for baseline
Cross-tolerance
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Pupil dilation
- Temperature regulation suppression
- Increased perspiration
- Nausea
- Increased heart rate
- Increased blood pressure
- Seizure
- Muscle twitching
- Spontaneous bodily sensations
- Difficulty urinating
- Excessive yawning
- Muscle contractions
- Increased salivation
- Increased bodily temperature
- Stamina intensification
Positive
- Analysis enhancement
- Cognitive euphoria
- Emotion enhancement
- Wakefulness
- Motivation enhancement
- Novelty enhancement
- Conceptual thinking
- Unity and interconnectedness
- Laughter fits
- Increased sense of humor
- Immersion intensification
Negative
- Memory suppression
- Thought loops
- Delusion
- Time distortion
- Thought acceleration
- Machinescapes
- Depth perception distortions
- Thought loop
- Existential self-realization
- Emotion intensification
- Focus intensification
Positive
- Tactile enhancement
- Color enhancement
- Pattern recognition enhancement
- Visual acuity enhancement
- Tracers
- Increased music appreciation
- Increased libido
- Bodily control enhancement
- Color shifting
- Auditory acuity enhancement
Negative
- Appetite suppression
- Changes in felt bodily form
- Drifting
- After images
- Geometric visual patterns
- Mild internal hallucinations
- Auditory hallucination
- Auditory distortion
- Diffraction
- Symmetrical texture repetition
- Scenery slicing
- External hallucination
- Internal hallucination
- Autonomous entity
- Perspective hallucination
- Tactile intensification