2-Chloroephenidine
Aliases: 2-cl-eph, 2-cl-ephenidine, 2-cl-diphenidine, 2chloroephenidine, 2clephenidine, 2-chloro-ephenidine
Categories
Summary
2-Chloroephenidine has the highest NMDA receptor affinity within the diphenidine family in vitro, though in vivo potency appears comparable to ephenidine. Very limited human safety data exists. Users report poorer urinary tract tolerance compared to other dissociatives and a steep dose-response curve above 150 mg. Bladder and kidney issues have been reported with chronic diarylethylamine use. Use extreme caution with dosing.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 100-130mg | 130-175mg | 175-200mg | 200mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 20-60 min | 30-60 min | 1-2.5 hrs | 2-4 hrs | 2-6 hrs | 180-0 min |
| Rectal | 10-20 min | 20-40 min | 1-2.5 hrs | 2-4 hrs | 2-6 hrs | 180-0 min |
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2–4 weeks for noticeable reduction
Effects
Positive
- Pain relief
- Stimulation
- Physical euphoria
- Spontaneous tactile sensations
Negative
- Numbness
- Loss of balance
- Increased heart rate
- Clumsiness in movement
- Physical disconnection
- Tactile disconnection
Positive
- Euphoria
- Conceptual thinking
- Cognitive euphoria
Negative
- Cognitive disconnection
- Motor control loss
- Depersonalization
- Derealization
- Anxiety
- Dissociation
- Time distortion
Positive
- Perception of bodily lightness
Negative
- Tactile suppression
- Double vision
- Acuity suppression
- Auditory suppression
- Visual disconnection
- Visual drifting
- Internal hallucinations
- Auditory distortion
- Auditory hallucinations