At the time I'm writing this, I still feel a bit odd and dissociated from the real world, so I apologize if I make any mistakes in my grammatic. It was morning, 7th of January, and I just called in sick from work because, well, simply I did not really feel like it today, my package that I ordered, 6 grams of 2-Methylme...
2-MMC
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 5 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 5 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: Ortho, 2-methyl mc, Orthophedrone, Orthomephedrone, 2mmc, ortomephedrone, 2-methylmethcathinone, 2methylmethcathinone, 2-mephedrone
Summary
2-MMC (2-Methylmethcathinone, also known as Ortho-Mephedrone) is a synthetic stimulant of the cathinone class. It acts as a serotonin-norepinephrine-dopamine releasing agent with higher affinity for DAT and NET than SERT, producing more focused, amphetamine-like stimulation with less euphoria than its isomers 3-MMC and 4-MMC.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 20-50mg | 50-100mg | 100-135mg | 135mg+ |
| Insufflated | 5-15mg | 15-40mg | 40-80mg | 80mg+ |
| Intravenous | 1-10mg | 10-30mg | 30-50mg | 50mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 20-45 min | 30-60 min | 1-2 hrs | 1-2 hrs | 2.83-5.75 hrs |
| Insufflated | 1-5 min | 5-15 min | 1-2 hrs | 1-2 hrs | 2.1-4.33 hrs |
| Rectal | 10-20 min | 20-40 min | 1-2 hrs | 1-2 hrs | 2.5-5 hrs |
| Intravenous | 1-10 sec | 5-10 min | 15-30 min | 30-45 min | 1-3 hrs |
Effect Profile
4 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Empathogen
4.7
Moderate+
5/10
Strong sensory enhancement with moderate stimulation, mild euphoria, low empathy
Empathy / Social Openness
×3
3
empathy & sociability
Euphoria / Mood Elevation
×2
5
euphoria
mood lift
Stimulation
×1
6
stimulation
increased energy
increased heart rate
Sensory Enhancement
×1
8
music appreciation enhancement
tactile enhancement
increased libido
Stimulant
5.5
Strong
6/10
Moderate euphoria, anxiety/jitters, and focus with mild stimulation
Stimulation / Energy
×3
5
stimulation
increased energy
Euphoria / Mood Lift
×2
7
euphoria
mood lift
motivation enhancement
Focus / Productivity
×2
6
cognitive enhancement
analysis enhancement
motivation enhancement
Anxiety / Jitters
×1
7
anxiety
increased heart rate
sweating
Based on reports from:
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 2-MMC there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
⬇ Download import file
Import this file as custom substances
and you get "2-MMC (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Name
2-MMC
Unit
mg
Description
2-MMC Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 20-50 · common 50-100 · strong 100-135 · heavy 135+ Insufflated dose (mg): light 5-15 · common 15-40 · strong 40-80 · heavy 80+ Rectal dose (mg): threshold 10-20 Intravenous dose (mg): threshold 1 · light 1-10 · common 10-30 · strong 30-50 · heavy 50+ Oral duration: onset 20-45m · come-up 0.5-1h · peak 1-2h · offset 1-2h · total 2.83-5.75h · after-effects 2-8h Insufflated duration: onset 1-5m · come-up 5-15m · peak 1-2h · offset 1-2h · total 2.1-4.33h · after-effects 2-8h Rectal duration: onset 10-20m · come-up 20-40m · peak 1-2h · offset 1-2h · total 2.5-5h · after-effects 2-8h Intravenous duration: onset 1-10s · come-up 5-10m · peak 15-30m · offset 30-45m · total 1-3h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 75 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Tolerance Decay
Full tolerance
1h
Half tolerance
4d
Baseline
~5d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 4 Erowid experience reports
Positive Effects 4
Euphoria
75.0%
70%
Music Enhancement
75.0%
70%
Focus Enhancement
75.0%
70%
Stimulation
75.0%
70%
Adverse Effects 0
Combinations
Cross-Check 2-MMC with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 4 reports 1 positive 2 neutral 1 cautionary visit
I ordered 2 grams of 2-MMC crystals from some Dutch site to just have some fun with my friends for the weekend, it took like 4 days to come, and I am very excited for this shit, decided to write a report since I didn't find much information about it and thought it would be helpful for people that are interested in tryi...
First and foremost, this stuff up the nose hurts like a motherfucker. If 4-FA is a 10/10 on the pain scale (which it is) then I'd put 2-MMC around an 8-8.5/10. That said the burn subsides within a minute or two. The drip is surprisingly not terrible, kinda taste like adderall but not quite as sweet.
Function Variant of 3-MMC I received my package of 2-MMC today and decided to write this report as there is hardly any info about this substance online. The recent Dutch ban of 3-MMC has resulted in RC vendors marketing 2-MMC as an alternative.
2-MMC's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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