Summary
2-PA is an extremely obscure beta-keto phenethylamine with almost no documented human use. TripSit describes it as amphetamine with the alpha-methyl replaced by a ketone. Human data are limited to a handful of online self-experiments; no formal pharmacology, toxicology, or safety studies exist. Assume cathinone-like risks including cardiotoxicity, neurotoxicity, tachycardia, vasoconstriction, and hyperthermia. Always perform an allergy test (≤5 mg), use an accurate milligram scale, avoid consecutive-day use, and stay hydrated.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-25mg | 25-50mg | 50-100mg | 100+mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 15-45 min | 30-60 min | 1-2 hrs | 1-2 hrs | 1-10 hrs | 180-0 min |
| Insufflated | 5-15 min | 15-30 min | 1-2 hrs | 1-2 hrs | 1-10 hrs | 180-0 min |
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Effects
Positive
- Stimulation
Negative
- Teeth grinding
- Vasoconstriction
- Insomnia
- Increased heart rate
- Pupil dilation
- Nausea
- Restlessness
- Sedation
- Decreased appetite
Positive
- Euphoria
- Focus enhancement
- Motivation enhancement
- Sociability enhancement
- Cognitive euphoria
Negative
- Anxiety
- Confusion
- Compulsive redosing
- Time distortion
- Talkativeness
Positive
- Color enhancement
- Increased music appreciation
- Brightened colour
Negative
- Appetite suppression
- Light sensitivity
- Disinhibition
- Dehydration
- Dulled perception
- Closed/Open eye visuals
- Drifting