Summary
2-TFMXP is the 2-trifluoromethyl analogue of methoxphenidine (MXP). Very little formal pharmacology is published; all dosing is extrapolated from user reports and structural activity relationships. Compared with MXP it appears 1.5-2× more potent and noticeably more stimulating with increased mania potential. Marked inter-individual variability exists; some users report minimal effects below 30 mg while others reach full dissociation at 25 mg. Start low and titrate carefully.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | - | - | - | 70+mg(NOTRECOMMENDED)+ |
| Sublingual | - | - | - | 60+mg(NOTRECOMMENDED)+ |
| Insufflated | - | - | - | 45+mg(NOTRECOMMENDED)+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 20-60 min | 30-60 min | 1.5-4 hrs | 2-4 hrs | 24 hrs |
| Sublingual | 10-30 min | 20-45 min | 1.5-4 hrs | 2-4 hrs | 24 hrs |
| Insufflated | 5-15 min | 15-30 min | 1.5-4 hrs | 2-4 hrs | 24 hrs |
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2–4 weeks for noticeable reduction
Effects
Positive
- Stimulation
- Physical euphoria
- Spontaneous tactile sensations
- Pain relief
Negative
- Numbness
- Loss of balance
- Increased heart rate
- Clumsiness in movement
- Tactile disconnection
- Physical disconnection
Positive
- Euphoria
- Conceptual Thinking
Negative
- Depersonalization
- Derealization
- Motor Control Loss
- Memory Suppression
- Anxiety
- Time Distortion
- Consciousness Disconnection
- Dissociation
Positive
- Perception of Bodily Lightness
- Increased Music Appreciation
- Perception of bodily lightness
Negative
- Tactile Suppression
- Spatial Disorientation
- Tactile suppression
- Visual Disconnection
- Internal Hallucination
- Visual disconnection
- Internal hallucinations