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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    25C-NBOH Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 4 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 19 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Tentative
    • classified Research-chemical

    Aliases: 2c-c-nboh, Nboh-2c-c

    Summary dose.wiki TripSit PsychonautWiki

    25C-NBOH is a novel research chemical with extremely limited human use history and assumed similar toxicity to 25C-NBOMe, which has been linked to multiple deaths. This substance must NEVER be insufflated (snorted) due to high risk of fatal overdose. Compounds of the NBOH family are NOT orally active and must be administered sublingually, holding in the mouth for 15-25 minutes.

    Dose Information dose.wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Sublingual 250-500ยตg 500-750ยตg 750-1000ยตg 1400-2000ug+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Sublingual 15-45 min 30-90 min 1.5-3 hrs 2-4 hrs 72-144 hrs 4-6 hrs

    Effect Profile

    4 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.4
    Intense 8/10

    Strong visuals, auditory effects, body load, and headspace

    Visual Intensity ×3
    10
    colour enhancement drifting tracers synaesthesia pattern recognition enhancement colour shifting +6 more
    Headspace Depth ×3
    9
    conceptual thinking recursion emotion enhancement personal bias suppression time distortion confusion
    Auditory Effects ×1
    10
    auditory distortion auditory hallucination synaesthesia
    Body Load / Somatic Effects ×1
    10
    nausea vasoconstriction temperature regulation suppression muscle tension increased heart rate
    Based on reports from:

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes 25C-NBOH, but its built-in data can be thinner than ours. Importing this file adds a separate "25C-NBOH (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "25C-NBOH (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7โ€“14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects dose.wiki TripSit PsychonautWiki

    Positive
    • Stimulation
    • Mental/physical stimulation
    Negative
    • Nausea
    • Vasoconstriction
    • Pupil dilation
    • Restlessness
    • Sweating/chills
    • Muscle tension
    • Insomnia
    • Headache
    • Muscle cramp
    • Stomach cramp
    • Temperature regulation suppression
    • Increased heart rate
    • Increased blood pressure
    • Seizure
    • Abnormal heartbeat
    • Dry mouth
    Neutral
    • Mouth Numbing
    • Decreased appetite
    • Difficulty urinating
    • Frequent urination
    • Restless legs
    • Spontaneous bodily sensations
    • Muscle contractions
    • Increased bodily temperature
    • Brightness alteration
    Positive
    • Analysis Enhancement
    • Conceptual Thinking
    • Empathy, Affection, And Sociability Enhancement
    • Emotion Enhancement
    • Wakefulness
    • Euphoria
    • Empathy
    • Insight
    • Novelty enhancement
    • Unity and interconnectedness
    • Laughter fits
    • Increased sense of humor
    • Immersion intensification
    Negative
    • Anxiety
    • Paranoia
    • Confusion
    • Memory suppression
    • Amnesia
    Neutral
    • Thought Acceleration
    • Feelings Of Impending Doom
    • Time Distortion
    • Change in perception
    • Ego softening
    • Machinescapes
    • Depth perception distortions
    • Recursion
    • Perspective distortion
    • Personal bias suppression
    • Peripheral information misinterpretation
    • Existential self-realization
    • Emotion intensification
    Positive
    • Perception Of Bodily Lightness
    • Visual Acuity Enhancement
    • Colour Enhancement
    • Pattern Recognition Enhancement
    • Colour Shifting
    • Tracers
    • Increased Music Appreciation
    • Synaesthesia
    • Brightened colour
    • Enhanced tactile sensation
    • Increased libido
    • Color enhancement
    • Color shifting
    • Auditory acuity enhancement
    Negative
    • Dehydration
    • Appetite suppression
    Neutral
    • Spontaneous Physical Sensations
    • Drifting
    • Symmetrical Texture Repetition
    • Closed/Open eye visuals
    • Auditory hallucination
    • Auditory distortion
    • Magnification
    • Diffraction
    • Scenery slicing
    • Internal hallucination
    • After images
    • Gustatory hallucination
    • Color tinting
    • Perspective hallucination
    • Visual processing deceleration
    • Color replacement

    Combinations TripSit

    Cross-Check 25C-NBOH with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 4 reports 3 positive 1 neutral visit
    The Five of Us... neutral exp #102297

    NBOH for Dummies [Erowid Note: The term "acid" has been used as a common name for d-LSD since the 1960s. Although confusion associated with newer psychoactive substances has lead some people to use the term "acid" to refer to anything LSD-like or anything psychedelic on blotter or sold in drops, we believe this represe...

    ModestMouse · 1 hit sublingual
    Dipping the Toe positive exp #101803

    23:10 Administered half-tab (500ug) 25C-NBOH, sub-lingual. 23:30 (T+20mins) Not feeling any effects yet. Still have tab between top lip and gum. Playing some piano, just improvising some ideas. I think for this trip I will leave the record button on for the duration.

    F. Eastwood · smoked / 500 ug buccal
    Gentle Clear-Headed and Uplifting positive exp #102277

    Background: 31 year old male, 190 lb/86 kg body weight. Past experience includes DXM, cannabis, psilocybin, LSD, salvia, and MDMA. What follows is my first research chemical experience. Both trials were at home, with no plans made. I take Wellbutrin 450 mg daily.

    finpat · 450 mg oral / 500 ug buccal / 1 mg sublingual
    Introspective Gold positive exp #102984

    I have had a reasonable experience with psychedelics over the two years prior to dosing 25-c NBOH. These included: DMT, Psilocybin, Muscimol, LSD, 25-i NBOH and MDA. I consumed no drugs of any kind for 2 weeks prior to dosing. [0:00] - Dose of 1000ug administered sub-lingually via a blotter on an empty stomach.

    S.B. · 1 mg sublingual

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