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    Disclaimer
    ☠ This substance has been associated with serious adverse events including fatalities. Use extreme caution.
    ☢ This substance has an extremely narrow safety margin. Small dosing errors can lead to life-threatening effects.
    ☠ NBOMe compounds are active at sub-milligram doses and have been linked to numerous deaths. They are frequently mis-sold as LSD. Always test substances before use.
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    25D-NBOMe

    Aliases: 25d, N-bomb, 2c-d-nbome, Nbome-2c-d, Divination

    Psychedelic Research-chemical

    Summary TheDrug.Wiki TripSit PsychonautWiki

    25D-NBOMe is a highly potent research chemical with an extremely narrow margin between active and potentially lethal doses. The compound is not orally active and must be administered sublingually or via other mucosal routes. Insufflation is strongly discouraged as this route has been associated with numerous fatalities across the NBOMe series.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Sublingual 300-800µg 800-1000µg 1000-1200µg 1200µg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Sublingual 20-40 min 1-2 hrs 1-2 hrs 6-6 hrs 2.3-4.7 hrs
    Insufflated 5-15 min 45-90 min 1-2 hrs 4-6 hrs 1.8-3.8 hrs

    Effect Profile

    12 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.0
    Intense 8/10

    Strong visuals, auditory effects, body load, and headspace

    Visual Intensity ×3
    10
    color enhancement drifting tracers synaesthesia pattern recognition enhancement color shifting +5 more
    Headspace Depth ×3
    8
    conceptual thinking emotion enhancement perspective distortions personal bias suppression time distortion confusion
    Auditory Effects ×1
    10
    auditory enhancement auditory distortion auditory hallucination synaesthesia
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea temperature regulation suppression vasoconstriction muscle tension increased heart rate
    Based on reports from:
    Erowid Experience Reports PsychonautWiki 25D-NBOMe
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use (serotonergic psychedelic)
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects Erowid

    Aggregated from 12 Erowid experience reports

    Positive Effects 8

    Color Enhancement 75.0% 70%
    Music Enhancement 58.3% 70%
    Focus Enhancement 50.0% 70%
    Body High 50.0% 70%
    Empathy 41.7% 70%
    Tactile Enhancement 33.3% 70%
    Introspection 33.3% 70%
    Stimulation 25.0% 70%

    Adverse Effects 5

    Anxiety 41.7% 70%
    Increased Heart Rate 33.3% 70%
    Muscle Tension 25.0% 70%
    Confusion 25.0% 70%
    Thought Loops 25.0% 70%

    Combinations TripSit

    25D-NBOMe's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki 📖 TripSit