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    Disclaimer
    โ˜  This substance has been associated with serious adverse events including fatalities. Use extreme caution.
    โ˜ข This substance has an extremely narrow safety margin. Small dosing errors can lead to life-threatening effects.
    โ˜  NBOMe compounds are active at sub-milligram doses and have been linked to numerous deaths. They are frequently mis-sold as LSD. Always test substances before use.
    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    25D-NBOMe Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 4 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 19 combo interactions documented
    • PubChem toxicity data
    • classified Research-chemical

    Aliases: 25d, N-bomb, 2c-d-nbome, Nbome-2c-d, Divination

    Summary TheDrug.Wiki TripSit PsychonautWiki

    25D-NBOMe is a highly potent research chemical with an extremely narrow margin between active and potentially lethal doses. The compound is not orally active and must be administered sublingually or via other mucosal routes. Insufflation is strongly discouraged as this route has been associated with numerous fatalities across the NBOMe series.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Sublingual 300-800ยตg 800-1000ยตg 1000-1200ยตg 1200ยตg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Sublingual 20-40 min 1-2 hrs 1-2 hrs 6 hrs 4-6 hrs

    Effect Profile

    12 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.0
    Intense 8/10

    Strong visuals, auditory effects, body load, and headspace

    Visual Intensity ×3
    10
    color enhancement drifting tracers synaesthesia pattern recognition enhancement color shifting +5 more
    Headspace Depth ×3
    8
    conceptual thinking emotion enhancement perspective distortions personal bias suppression time distortion confusion
    Auditory Effects ×1
    10
    auditory enhancement auditory distortion auditory hallucination synaesthesia
    Body Load / Somatic Effects ×1
    10
    nausea temperature regulation suppression vasoconstriction muscle tension increased heart rate

    Tolerance

    Build-up develops rapidly after a single use (serotonergic psychedelic)
    Reset 7โ€“14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects Erowid

    Aggregated from 12 Erowid experience reports

    Positive Effects 8

    Color Enhancement 75.0% 70%
    Music Enhancement 58.3% 70%
    Focus Enhancement 50.0% 70%
    Body High 50.0% 70%
    Empathy 41.7% 70%
    Tactile Enhancement 33.3% 70%
    Introspection 33.3% 70%
    Stimulation 25.0% 70%

    Adverse Effects 5

    Anxiety 41.7% 70%
    Increased Heart Rate 33.3% 70%
    Muscle Tension 25.0% 70%
    Confusion 25.0% 70%
    Thought Loops 25.0% 70%

    Combinations TripSit

    Cross-Check 25D-NBOMe with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 1 positive 7 neutral visit
    Meditation Insight Oh Fuck Me positive exp #108290

    I have a fair amount of experience with fun but had never taken a ride on the 25D-NBOMe HCl (1000ยตg) before. I put one tab between cheek and gum, straightened up the house, put up some Post-It notes reminding me who I am, where I was, and what I'd done. Just in case.

    notspan · buccal
    Plugging for Science neutral exp #100881

    This report comes from an experience I had last night while undergoing a trial of 25D-nBOME in combination with Cannabis. When I decided to acquire 25D I did so for a few reasons. First it was new to me and I am quite open to new psychedelic experiences. Second, one gram only cost $120.

    somekidyouknow · rectal / 1 bowl smoked / 1 bowl smoked / 1 bowl smoked
    Exploring the Present in the Future neutral exp #107803

    Due to the small amount of information available online about this substance, and the strong experience I had, I felt it so necessary to record what happened that I am writing this the next morning. I currently have a headache, but Iย’m otherwise happy and sober.

    ZLPer · 2 mg buccal
    Almost but Not Quite neutral exp #90995

    Note that as this report was written post-trip all timings are approximate. I had recently managed to get my hands on some 25D-NBOMe from a trusted vendor, as I didn't have an accurate scale at the time and didn't feel like going through the hassle of volumetric measurement, I opted to buy the pre-laid blotter offered...

    Zilpe · 1.6 mg buccal
    A Much Warpier High neutral exp #105062

    Acid Ecstasy the 25D Expeirence When I first took 25D I had heard about it after trying LSD. I originate from Humboldt, CA where acid is readily available but in March of 2013 I moved just northwest of Portland, OR where LSD is much harder to obtain and research chemicals like the NBOMe's are very available.

    HumboldtDude707 · 1 mg sublingual / smoked / smoked / 1 hit smoked
    Powerful Trip neutral exp #104931

    I obtained blotters with 25D and having experience with 25C I will compare this compound to 25C. Also I am writing this post-trip but it will be accurate because I remember the trip almost entirely. 0:35 Put it in my gums and about 35 minutes later I began feeling the effects.

    Cartoons · 3.2 mg buccal
    Almost Lost It neutral exp #104545

    Yesterday I decided to pick up a coulple hits of 25d from a friend. I had heard 25d was one of the weaker NBOMe's and being experienced with 25i, b, and c in high doses I decided to take both hits. I started to feel it within 30 mins or so.

    AppLE
    25D-NBOMelated neutral exp #91460

    So I finally got around to experimenting with this one. I put two 800 mcg blotters (25d-nbome) between my upper gum and cheek. I tried to swallow my spit as little as possible but I ended up doing it a tad bit too often; probably resulting in a lighter experience.

    Psyke · 1600 ug buccal
    Bluelight 2 threads 2 neutral visit
    25d Nbome First Time 2 4 Mg neutral

    25D-NBOMe First time - 2.4 mg. No Title... *I took a very large dose. Having never experimented with compound before, this is very foolish, but I had faith I'd be okay. Start low. Gradually build up. Then practice methods of titrating dose, perhaps. That's what I'm going to do, if I decide to experiment again.

    scraped 2026-03-14
    25d Nbome First Time First Time 25d Trip Report neutral

    Hello everyone, I wanna start by giving some info on myself, I'm a male 22 yo 170 pounds 5'11, I'm pretty experienced in drugs as far as psycodelic or hallucinations go ive done LSD, Mushrooms, 25I 2-cb and most recently 25d. I had one of the strangest experiences in my life when I took 25d.

    scraped 2026-03-14

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