Summary
25I-NBOH is approximately 2-3 times less potent than 25I-NBOMe but significantly more potent than 2C-I. Not orally active; must be administered sublingually or buccally. Extreme vasoconstriction and cardiovascular strain reported at higher doses. The compound is chemically labile and degrades into 2C-I under heat and standard GC-MS analysis. Blotters sold as LSD have been confirmed to contain 25I-NBOH; always use reagent testing.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Sublingual | 200-500µg | 500-900µg | 900-1400µg | 1400µg+ |
| Buccal | 200-500µg | 500-900µg | 900-1400µg | 1400µg+ |
| Oral | 416ug-766 | 800-1400µg | 1400ug-2000 | 2000µg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Sublingual | 15-60 min | 30-90 min | 2.0-3.5 hrs | 1.5-2.5 hrs | 3.0-12.0 hrs | 5.0-10.0 hrs |
| Buccal | 15-60 min | 30-90 min | 2-3.5 hrs | 1.5-2.5 hrs | 3-12 hrs | 300-0 min |
| Oral | 19-45 min | 30-90 min | 2.0-3.5 hrs | 1.5-2.5 hrs | 3.0-12.0 hrs | 5.0-10.0 hrs |
Tolerance
Build-up
develops rapidly after a single use (serotonergic psychedelic)
Reset
7–14 days for baseline
Effects
Positive
- Stimulation
- Physical Euphoria
- Mental/physical stimulation
Negative
- Nausea
- Temperature Regulation Suppression
- Increased Heart Rate
- Increased Blood Pressure
- Vasoconstriction
- Pupil Dilation
- Restlessness
- Sweating/chills
- Muscle tension
- Insomnia
- Headache
- Muscle cramp
- Stomach cramp
- Seizure
- Abnormal heartbeat
- Dry mouth
- Mouth Numbing
- Decreased appetite
- Difficulty urinating
- Frequent urination
- Restless legs
- Spontaneous bodily sensations
- Muscle contractions
- Increased bodily temperature
- Brightness alteration
Positive
- Analysis Enhancement
- Conceptual Thinking
- Empathy Enhancement
- Emotion Enhancement
- Wakefulness
- Euphoria
- Empathy
- Insight
- Empathy, affection and sociability enhancement
- Novelty enhancement
- Unity and interconnectedness
- Laughter fits
- Increased sense of humor
- Immersion intensification
Negative
- Anxiety
- Confusion
- Paranoia
- Thought deceleration
- Memory suppression
- Amnesia
- Thought Acceleration
- Time Distortion
- Change in perception
- Ego softening
- Machinescapes
- Depth perception distortions
- Recursion
- Perspective distortion
- Personal bias suppression
- Peripheral information misinterpretation
- Existential self-realization
- Feelings of impending doom
- Emotion intensification
Positive
- Perception Of Bodily Lightness
- Visual Acuity Enhancement
- Colour Enhancement
- Pattern Recognition Enhancement
- Tracers
- Brightened colour
- Enhanced tactile sensation
- Synaesthesia
- Increased libido
- Color enhancement
- Increased music appreciation
- Color shifting
- Auditory acuity enhancement
Negative
- Dehydration
- Appetite suppression
- Spontaneous Physical Sensations
- Drifting
- Symmetrical Texture Repetition
- Internal Hallucination
- Closed/Open eye visuals
- Auditory hallucination
- Auditory distortion
- Magnification
- Diffraction
- Scenery slicing
- After images
- Gustatory hallucination
- Color tinting
- Perspective hallucination
- Visual processing deceleration
- Color replacement