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25N-NBOMe Stats & Data

Psychedelic Research-chemical

25n N-bomb 2c-n-nbome Nbome-2c-n 2-c-n-nbome

PubChem CID 118536028

NPS DataHub

MW346.38

FormulaC18H22N2O5

CAS1354632-03-3

IUPAC2-(2,5-dimethoxy-4-nitrophenyl)-N-[(2-methoxyphenyl)methyl]ethanamine

SMILESCOc1ccccc1CNCCc1cc(OC)c(N(=O)=O)cc1OC

InChIKeyTXCKTIBHURMASQ-UHFFFAOYSA-N

Phenethylamines; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen

Chemical Class Phenethylamine

Psychoactive Class Psychedelic

Receptor Profile

Receptor Actions

Agonists

5-HT2A receptor agonist (full)

5-HT2C receptor agonist (full)

5-HT2B receptor agonist (partial)

Other

dopamine transporter phosphorylation (increases extracellular dopamine)

Subjective Effects

Physical

The physical effects of 25N-NBOMe can be broken down into several components which progressively intensify proportional to dosage.

Wakefulness
Stimulation: In terms of its effects on the energy levels of the tripper, 25N-NBOMe is quite stimulating, and leftover stimulation can linger up to 10 hours even after the trip subsides.
Vasoconstriction
Tactile enhancement
Bodily control enhancement: When combined with stimulation, this component manifests as a strong drive to partake in physical activities.
Runny nose: 25N-NBOMe may cause a runny nose and increased mucus production in some users.
Nausea: Users (especially those prone to it) may experience nausea during the come up. The nausea will subside over the peak.
Increased heart rate
Pupil dilation

Cognitive

The cognitive effects of 25N-NBOMe can be described as quite reminiscent to that of 25C-NBOMe. They can be broken down into several components which progressively intensify proportional to dosage.

Time distortion
Analysis enhancement: This component is introspection dominant.
Conceptual thinking
Thought connectivity
Feelings of self-design
Novelty enhancement
Cognitive euphoria
Laughter
Memory suppression: (Ego death)

Sensory

Auditory

Enhancements
Distortions
Hallucinations

Visual · Distortions

Symmetrical texture repetition
3-Dimensional textures
Drifting: (Melting, flowing, breathing and morphing) - In comparison to other psychedelics, this effect can be described as highly detailed, slow and smooth in motion, static in appearance and unrealistic/cartoon-like in style.

Visual · Enhancements

Visual acuity enhancement
Colour enhancement
Pattern recognition enhancement

Visual · Hallucinatory States

Transformations
Internal hallucinations: (Autonomous entities; settings, sceneries, and landscapes; alterations in perspective and scenarios and plots) - 25N-NBOMe is capable of producing a full range of hallucinatory states within the level 1 - 3 range extremely consistently. Level 4 hallucinatory breakthroughs are reported, but very uncommon and inconsistent in comparison to other more commonly used psychedelics such as psilocin, 2C-E and DMT. This effect is more common within dark environments and can be described as internal in its manifestation, lucid in believability, interactive in style and of no particular theme in content or style.

Forked from Subjective Effect Documentation by Josie Kins, September 2015. Via dose.wiki (CC0).

Toxicity

PsychonautWiki

The toxicity and long-term health effects of recreational 25N-NBOMe use have not been studied in any scientific context and the exact toxic dosage is unknown. This is because 25N-NBOMe is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried 25N-NBOMe suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Users should be very careful and consider that ingesting 2mg+ of NBOMe series chemicals have proven fatal in some cases. Although there are no reported deaths caused by 25N-NBOMe at this time, it is a rare research chemical with very little history of human usage and is therefore potentially fatal at heavy dosages.

Effect Profile

Curated + 2 Reports

Psychedelic 7.5

Strong visuals, auditory effects, and body load with moderate headspace

Visual Intensity×3

Headspace Depth×3

Auditory Effects×1

Body Load / Somatic Effects×1

Based on reports from:

Erowid Experience Reports PsychonautWiki 25N-NBOMe

Tolerance & Pharmacokinetics

drugs.wiki

Tolerance Decay

Full tolerance 1h Half tolerance 10d Baseline ~14d

Experience Report Analysis

Erowid

2 Reports

2014–2015 Date Range

2 With Age Data

Demographics

Gender Distribution

Age Distribution

Reports Over Time

Read full reports on Erowid →

Legal Status

Country	Status	Notes
Austria	25N-NBOMe is illegal to possess, produce and sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich).
Brazil	Possession, production and sale is illegal as it is listed on Portaria SVS/MS nº 344.
Germany	25N-NBOMe is controlled under Anlage I BtMG (Narcotics Act, Schedule I) as of June 9, 2016.	It is illegal to manufacture, possess, import, export, buy, sell, procure or dispense it without a license.
Hungary	25N-NBOMe is illegal in Hungary.
Latvia	25N-NBOMe is a Schedule I controlled substance.
Sweden	The Riksdag added 25N-NBOMe to Narcotic Drugs Punishments Act under swedish schedule I ("substances, plant materials and fungi which normally do not have medical use") as of January 16, 2015, published by Medical Products Agency (MPA) in regulation LVFS 2014:11 listed as 25N-NBOMe, and 2-(2,5-dimetoxi-4-nitrofenyl)-N-(2-metoxibensyl)etanamin.
Switzerland	25N-NBOMe is a controlled substance specifically named under Verzeichnis E.
United Kingdom	This substance is a Class A drug in the United Kingdom as a result of the N-benzylphenethylamine catch-all clause in the Misuse of Drugs Act 1971.
United States	25N-NBOMe is illegal in Alabama.

References

Data Sources

Cited References

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