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    Disclaimer
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    ⚠ This substance involves MAOI activity. Dangerous interactions can occur with many common foods and medications. Research contraindications thoroughly.

    2C-T Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 3 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 17 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Tentative
    • classified Research-chemical

    Aliases: Tesseract, 2ct

    Summary dose.wiki TripSit PsychonautWiki

    2C-T is a lesser-known research chemical with very limited human use history and minimal scientific data on its pharmacology, metabolism, and toxicity. It is structurally similar to 2C-T-2 and 2C-T-7 and may possess MAOI properties, making it potentially more dangerous when combined with other serotonergic substances. The substance is illegal in many jurisdictions including the United States (Schedule I), United Kingdom (Class A), and Canada (Schedule III).

    Perspectives

    “Poetry was an easy and natural thing. Both the reading of it and the writing of it. This is a potential MDMA substitute since it opens things up but it doesn’t do anything to get in the way.”

    Dose Information dose.wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 40-60mg 60-100mg 100-120mg 125mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Oral 30-45 min 0.5-1.92 hrs 1-2 hrs 1-2 hrs 2-6 hrs

    Effect Profile

    2 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 7.2
    Strong+ 7/10

    Strong visuals, auditory effects, and body load with moderate headspace

    Visual Intensity ×3
    10
    colour enhancement drifting tracers pattern recognition enhancement scenery slicing color shifting +2 more
    Headspace Depth ×3
    6
    conceptual thinking emotion enhancement personal bias suppression time distortion
    Auditory Effects ×1
    8
    auditory distortion auditory hallucination
    Body Load / Somatic Effects ×1
    8
    nausea vasoconstriction muscle tension increased heart rate
    Empathogen 3.0
    Light+ 3/10

    Strong sensory enhancement with moderate stimulation, low euphoria

    Empathy / Social Openness ×3
    0
    Euphoria / Mood Elevation ×2
    2
    emotion enhancement
    Stimulation ×1
    7
    stimulation wakefulness restlessness increased heart rate
    Sensory Enhancement ×1
    10
    tactile enhancement colour enhancement visual acuity enhancement

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes 2C-T, but its built-in data can be thinner than ours. Importing this file adds a separate "2C-T (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "2C-T (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects dose.wiki PsychonautWiki

    Positive
    • Stimulation
    • Mental/physical stimulation
    Negative
    • Nausea
    • Vasoconstriction
    • Pupil dilation
    • Increased heart rate
    • Restlessness
    • Muscle tension
    • Insomnia
    Neutral
    • Spontaneous Bodily Sensations
    Positive
    • Emotion Enhancement
    • Analysis Enhancement
    • Novelty Enhancement
    • Conceptual Thinking
    • Increased Sense of Humor
    • Immersion Enhancement
    • Wakefulness
    • Unity and interconnectedness
    • Immersion intensification
    Negative
    • Delusion
    • Memory suppression
    Neutral
    • Time Distortion
    • Personal Bias Suppression
    • Thought acceleration
    • Thought loop
    • Perception of interdependent opposites
    • Existential self-realization
    • Emotion intensification
    Positive
    • Tactile Enhancement
    • Bodily Control Enhancement
    • Increased Music Appreciation
    • Colour Enhancement
    • Visual Acuity Enhancement
    • Pattern recognition enhancement
    • Tracers
    • Color enhancement
    • Color shifting
    • Auditory acuity enhancement
    Neutral
    • Drifting
    • Auditory hallucination
    • Auditory distortion
    • Symmetrical texture repetition
    • Scenery slicing
    • Internal hallucination
    • Autonomous entity
    • After images
    • Perspective hallucination
    • Tactile intensification

    Combinations TripSit

    Cross-Check 2C-T with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 2 reports 1 neutral 1 cautionary visit
    Testing Sulfurous Waters cautionary exp #118461

    Substance: 2C-T HCl (2,5-dimethoxy-4-methylthiophenethylamine hydrochloride) Dosage: 53 mg p.o., dissolved in water Purity: mp range a bit wide, but bulk of it melts at 240 - 241 Β°C; material not (yet) recrystallised; ever so slightly off-white Age: mid 20s Weight: ~ 60 kg Intention: explore sub-PiHKAL dose of 2C-T Set...

    xdrc
    Mostly Harmless neutral exp #111102

    DOSES: T+00:00 2C-T 85 mg oral T+02:40 beer (one can) T+04:00 cannabis (one mini joint) WHO I AM 45 year old male, around 95 lbs, experienced. I've tried and loved all the classics (DMT, LSD, Mushrooms, Mescaline both from cactus and synthetic), many new classics (most 2C-x and DOx, MDMA), and several other widespread...

    bb
    Bluelight 2 threads 2 neutral visit
    2c T 53 Mg Testing The Sulfurous Waters neutral

    Substance: 2C-T HCl (2,5-dimethoxy-4-methylthiophenethylamine hydrochloride) Dosage: 53 mg p.o., dissolved in water Purity : mp range a bit wide, but bulk of it melts at 240 - 241 Β°C; material not (yet) recrystallised; ever so slightly off-white Age: mid 20s Weight: ~ 60 kg Intention: explore sub-PiHKAL dose of 2C-T Se...

    scraped 2026-03-14
    2c T 100mg 2nd Time Mr neutral

    A week after trying 2C-T for the first time at a dose of 50mg, I was eager to experience its full effects. I took 100mg and then started to play guitar. After 20 minutes or so, I started noticing the first effects coming on. Things were looking extra colorful and playing guitar was easier than usual.

    scraped 2026-03-14

    PiHKAL / TiHKAL Shulgin

    PiHKAL #39: 2C-T

    “Poetry was an easy and natural thing. Both the reading of it and the writing of it. This is a potential MDMA substitute since it opens things up but it doesn’t do anything to get in the way.”

    β€” Alexander Shulgin, PiHKAL (with 60 mg)

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