Summary
Human data are extremely limited; most information derives from small online self-reports and structural analogy to better-studied cathinones such as ethcathinone and 3-CMC. Meta-chlorinated cathinones have shown greater cytotoxicity in vitro compared with non-halogenated analogues; long-term neurotoxicity is plausible but unquantified. Pronounced vasoconstriction and hypertension observed; users with cardiovascular risk factors should avoid. Always confirm identity with reagent testing (Marquis reagent typically shows faint yellow-brown; Mecke shows olive-green) and ideally chromatography, as 3-CEC is sometimes mis-sold as 3-MMC or other cathinones. Due to short half-life, compulsive redosing is common; limit sessions to under 150 mg total, maintain hydration and electrolytes, supplement sleep, and allow at least 2 weeks between uses to reset tolerance and neurotransmitter stores.
Dose Information
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 15-40 min | 20-40 min | 1-2 hrs | 1-2 hrs | 2-6 hrs |
| Insufflated | 5-10 min | 10-20 min | 1-2 hrs | 1-2 hrs | 2-6 hrs |
Tolerance
Effects
- Stimulation
- Physical euphoria
- Increased heart rate
- Vasoconstriction
- Teeth grinding
- Perspiration
- Pupil dilation
- Insomnia
- Nausea
- Sedation
- Euphoria
- Focus enhancement
- Motivation enhancement
- Increased sociability
- Cognitive euphoria
- Anxiety suppression
- Anxiety
- Compulsive redosing
- Cognitive fatigue
- Depression
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Appetite suppression
- Light sensitivity
- Disinhibition
- Dehydration
- Double vision
- Dulled perception
- Visual disconnection