Summary
Cocaine (also known as benzoylmethylecgonine, and informally as coke, cola, snow, blow, white, among others) is a classical stimulant substance of the tropane class. It is a naturally-occurring alkaloid extracted from the leaves of two coca plant species; namely Erythroxylum coca and E. novogranatense that are native to South America. The mechanism of action involves increasing levels of serotonin, dopamine, and norepinephrine in the brain.[citation needed].
Perspectives
“The slippery slope to addiction does appear to be less obvious than for most other drugs in this class. Be careful with respect to this: very careful.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated BA 60-80% | 10-30mg | 30-60mg | 60-90mg | 90mg+ |
| Oral BA 33% | 13-75mg | 75-150mg | 150-225mg | 225mg+ |
| Intravenous | 2-5mg | 5-10mg | 10-15mg | 15mg+ |
| Smoked BA 90% | 5-15mg | 15-30mg | 30-45mg | 45mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Insufflated | 1-3 min | 4-10 min | 15-30 min | 30-60 min | 1.0-3.0 hrs | 10.0-90.0 hrs |
| Oral | 10-30 min | 15-30 min | 30-60 min | 30-60 min | 1.0-3.0 hrs | 60-90 min |
| Intravenous | 0-0 min | 1-1 min | 4-15 min | 10-19 min | 1.0-3.0 hrs | 60-90 min |
| Smoked | 0-0 min | 1-1 min | 3-4 min | 4-15 min | 1.0-3.0 hrs | 60-90 min |
Tolerance
Build-up
acute tolerance develops rapidly within a single session
Reset
short-term tolerance resets within days; sensitization may persist
Effects
Positive
- Stimulation
- Physical euphoria
- Elevated mood
- Bronchodilation
- Pain relief
Negative
- Increased heart rate
- Nausea
- Abnormal heartbeat
- Increased blood pressure
- Increased perspiration
- Teeth grinding
- Temporary erectile dysfunction
- Vasoconstriction
- Mouth numbing
- Raised heartrate
- Numbing effects depending on ROA
Positive
- Euphoria
- Cognitive euphoria
- Increased confidence
- Motivation enhancement
- Focus enhancement
- Wakefulness
Negative
- Compulsive redosing
- Anxiety
- Paranoia
- Irritability
- Increase in irritability
- Cognitive fatigue
- Depression
- Thought deceleration
- Ego inflation
- Thought acceleration
- Time compression
- Hyper-inflated ego
- Thought organization
Positive
- Increased libido
- Auditory enhancement
Negative
- Disinhibition
- Appetite suppression
- Dehydration
- Tactile hallucination
- Drifting
- Internal hallucination
- Auditory hallucinations
- Internal hallucinations