Doing drugs for the past 7 years with proper tolerance 2+week breaks. Might call myself a journeyman by this moment. Ate a slight breakfest ~1000cal. Can't say how much of 3-CMC I took as I don't know the total initial amount I purchased. The pack didn't have the weight and I don't have scales.
3-CMC
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
- classified Tentative
- classified Research-chemical
Aliases: Clophedrone, 3-chloromethcathinone, 3cmc
Summary
3-CMC is a meta-chlorinated cathinone with significant neurotoxic and cardiotoxic concerns. Animal studies demonstrate neurotoxicity in mice, and its structural similarity to known neurotoxins like 4-CMA raises serious safety concerns. The compound is chemically unstable and degrades to potentially more toxic metabolites.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 30-60mg | 60-100mg | 100-180mg | 180mg+ |
| Insufflated | 20-40mg | 40-80mg | 80-100mg | 100mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 30-90 min | 30-60 min | 60-90 min | 1-2 hrs |
| Insufflated | 10-30 min | 15-30 min | 30-60 min | 30-60 min |
Effect Profile
2 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Empathogen
6.0
Strong
6/10
Moderate empathy and stimulation with mild euphoria and sensory enhancement
Empathy / Social Openness
×3
7
empathy enhancement
sociability enhancement
increased sociability
Euphoria / Mood Elevation
×2
5
euphoria
mood lift
Stimulation
×1
6
stimulation
wakefulness
teeth grinding
Sensory Enhancement
×1
5
tactile enhancement
increased libido
Stimulant
3.2
Light+
3/10
Strong anxiety/jitters with mild stimulation and euphoria
Stimulation / Energy
×3
5
stimulation
wakefulness
Euphoria / Mood Lift
×2
5
euphoria
mood lift
Focus / Productivity
×2
0
Anxiety / Jitters
×1
9
anxiety
teeth grinding
bruxism
sweating
Based on reports from:
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Tolerance Decay
Full tolerance
2d
Half tolerance
10d
Baseline
~35d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Patterns inferred from stimulant/cathinone use reports: notable acute tachyphylaxis within a session, residual tolerance persisting days to weeks; robust evidence is lacking.
Cross-Tolerances
Effects
Positive
- Stimulation
- Increased energy/alertness
Negative
- Teeth grinding
- Increased perspiration
- Muscle spasms
- Weight loss
- Sweating
- Bruxism
- Decreased need for sleep
- Decreased appetite
- Disturbed sleep patterns
- Itchiness
Positive
- Euphoria
- Sociability enhancement
- Empathy enhancement
- Wakefulness
- Increased sociability
- Mood lift
Negative
- Anxiety
- Compulsive redosing
- Aggressiveness
- Excessive talking
- Moodiness
Positive
- Increased libido
- Tactile enhancement
- Increased music appreciation
- Tracers
Negative
- Appetite suppression
- Light sensitivity
- Dehydration
- Disinhibition
- Increased sexuality
- Visual and auditory hallucinations
Combinations
Cross-Check 3-CMC with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 2 reports 2 neutral visit
I have had a nice time in the beginning, very MDMA-ish, I did it nasal, small lines every 10 minutes, in one night I did around 0.7 to 0.9 Grams of the substance.
Bluelight 1 thread 1 neutral visit
Experience Report: 3-CMC Crystals Chemical Name (according to vendor) is 1-(3-chlorophenyl)-2-(methylamino)propan-1-one It has been very difficult to find information on this chemical, but if I come across anything else in my research, I will definitely post it here.
3-CMC's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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