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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    3,4-Dichloromethylphenidate

    Aliases: 3,4-ctmp, 3,4-dcmp, Dichloromethylphenidate, 34ctmp

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    Summary TheDrug.Wiki TripSit PsychonautWiki

    3,4-CTMP is approximately seven times more potent than methylphenidate and has a significantly longer duration of 6-18 hours. A critical safety concern is its agonist activity at 5-HT2B receptors, which can cause pulmonary hypertension and heart valve fibrosis with repeated use. Insufflation is strongly discouraged as the substance has low water solubility, is extremely caustic to nasal tissues, and has poor absorption leading to delayed onset that increases overdose risk. Users must use precise milligram scales due to the extremely low active doses. The very long onset (1-2 hours) and extended duration require careful dose timing to avoid unwanted sleep disruption and accidental overdoses from premature redosing.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 2-4mg 4-6mg 6-8mg 8mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Oral 1-2 hrs 3-6 hrs 4-8 hrs 2-24 hrs 240-0 min

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3โ€“7 days for acute tolerance; longer for full reset

    Effects TheDrug.Wiki TripSit PsychonautWiki

    Positive
    • Stimulation
    • Increased energy/alertness
    Negative
    • Increased Heart Rate
    • Vasoconstriction
    • Teeth Grinding
    • Headaches
    • Pupil Dilation
    • Temporary Erectile Dysfunction
    • Weight loss
    • Sweating
    • Bruxism
    • Headache
    • Increased blood pressure
    • Abnormal heartbeat
    • Stimulant psychosis
    Neutral
    • Decreased need for sleep
    • Decreased appetite
    • Disturbed sleep patterns
    • Itchiness
    • Spontaneous bodily sensations
    • Mouth numbing
    • Decreased blood pressure
    • Stamina intensification
    Positive
    • Focus Enhancement
    • Motivation Enhancement
    • Wakefulness
    • Analysis Enhancement
    • Euphoria
    • Increased sociability
    • Mood lift
    • Cognitive euphoria
    Negative
    • Anxiety
    • Aggressiveness
    • Emotion suppression
    • Dizziness
    • Depression
    • Paranoia
    • Irritability
    • Thought deceleration
    • Brain zaps
    • Cognitive fatigue
    • Motivation depression
    Neutral
    • Thought Acceleration
    • Time Distortion
    • Excessive talking
    • Moodiness
    • Ego inflation
    • Thought organization
    • Focus intensification
    Positive
    • Visual acuity enhancement
    • Increased music appreciation
    Negative
    • Appetite Suppression
    • Dehydration
    • Double vision
    • Disinhibition
    • Visual acuity suppression
    • Cognitive dysphoria
    Neutral
    • Increased sexuality
    • Visual and auditory hallucinations
    • Drifting
    • Optical sliding
    • Color tinting
    • Tactile intensification

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