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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    3,4-Dichloromethylphenidate

    Aliases: 3,4-ctmp, 3,4-dcmp, Dichloromethylphenidate, 34ctmp

    Stimulant Research-chemical

    Summary TheDrug.Wiki TripSit PsychonautWiki

    3,4-CTMP is approximately seven times more potent than methylphenidate and has a significantly longer duration of 6-18 hours. A critical safety concern is its agonist activity at 5-HT2B receptors, which can cause pulmonary hypertension and heart valve fibrosis with repeated use. Insufflation is strongly discouraged as the substance has low water solubility, is extremely caustic to nasal tissues, and has poor absorption leading to delayed onset that increases overdose risk.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 2-4mg 4-6mg 6-8mg 8mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Oral 1-2 hrs 3-6 hrs 4-8 hrs 2-24 hrs 8-16 hrs

    Effect Profile

    5 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 6.4
    Strong 6/10

    Strong anxiety/jitters, euphoria, and focus with mild stimulation

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    9
    euphoria cognitive euphoria mood lift motivation enhancement
    Focus / Productivity ×2
    9
    focus enhancement analysis enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety paranoia increased heart rate teeth grinding bruxism vasoconstriction +1 more
    Based on reports from:
    Erowid Experience Reports PsychonautWiki 3,4-Dichloromethylphenidate
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Effects Erowid

    Aggregated from 5 Erowid experience reports

    Positive Effects 2

    Focus Enhancement 80.0% 70%
    Stimulation 80.0% 70%

    Adverse Effects 1

    Increased Heart Rate 100.0% 70%
    3,4-Dichloromethylphenidate's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 TripSit 📖 PsychonautWiki