3,4-Dichloromethylphenidate Stats & Data
JUKMAYKVHWKRKY-CHWSQXEVSA-NPharmacology
DrugBankReceptor Profile
Receptor Actions
Toxicity
PsychonautWikiThe toxicity and long-term health effects of recreational 3,4-CTMP use do not seem to have been studied in any scientific context, and the exact toxic dosage is unknown. This is because 3,4-CTMP is a research chemical with very little history of human usage. Although anecdotal evidence from people who have tried 3,4-CTMP suggests that there are unlikely to be negative health effects attributed to simply trying the substance by itself at low to moderate doses, the agonist activity it displays for the 5-HT2B receptor is a cause for concern, as acute 5-HT2B agonism has been shown to result in a potentially dangerous and largely asymptomatic effect called pulmonary hypertension.
Effect Profile
Curated + 5 ReportsStrong anxiety/jitters, euphoria, and focus with mild stimulation
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Experience Report Analysis
ErowidDemographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 5 experience reports (5 Erowid)
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 2
Adverse Effects 1
Real-World Dose Distribution
62K DosesFrom 14 individual dose entries
Oral (n=7)
Insufflated (n=6)
Form / Preparation
Most common forms and preparations reported
References
Cited References
- Arunotayanun (2014) - 5-HT2B receptor activity
- Davidson et al. (2018) - Neurochemical assessment in rat nucleus accumbens
- Davies et al. (2004) - Synthesis and binding affinities
- Drugs-Forum: 3,4-CTMP Wiki
- Erowid: 3,4-Dichloromethylphenidate Experience Reports
- PsychonautWiki: 3,4-CTMP
- Rothman et al. (2000) - 5-HT2B receptors and cardiac valvulopathy
- Wikipedia: 3,4-Dichloromethylphenidate
- Davies et al. (2004) - Synthesis and binding affinities
- Davidson et al. (2018) - Neurochemical assessment in rat nucleus accumbens