At the time of this experience I was dabbling with LSD quite a bit during the prior 3 months. Although I kinda got tired of LSD as the lengthy duration and I feel that I can never go as deep as I can with psychedelic tryptamines. Therefore I decided that I would order a 1 gram of 4ACO DET from a trusted vendor.
4-AcO-DET
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- PubChem toxicity data
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- PubChem toxicity data
- classified Tentative
- classified Research-chemical
Aliases: Ethacetin, Ethylacybin, 4-acetoxy-det
Summary
4-AcO-DET is a rare psychedelic tryptamine first synthesized by Albert Hofmann in 1958. It is believed to act as a prodrug for 4-HO-DET (ethocin). Effects are similar to psilocin, though some users report it being more stimulating and anxiety-inducing than other 4-substituted tryptamines.
Perspectives
“4-AcO-DET is a short trip. It's less introspective and more outrospective. You find yourself hyperanalyzing everything.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-15mg | 15-20mg | 20-35mg | 35mg+ |
| Smoked | 5-10mg | - | - | - |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 19-60 min | 60-90 min | 1.5-3 hrs | 1-2 hrs |
| Smoked | - | 4-10 min | 10-19 min | 19-40 min |
Effect Profile
50 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 50 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
8.8
Intense+
9/10
Strong visuals, headspace, auditory effects, and body load
Visual Intensity
×3
10
color enhancement
tracers
drifting
visual enhancement
pattern recognition enhancement
color shifting
+3 more
Headspace Depth
×3
10
conceptual thinking
thought connectivity
emotion enhancement
personal bias suppression
time distortion
Auditory Effects
×1
10
auditory distortion
auditory hallucination
Body Load / Somatic Effects
×1
10
nausea
bodily pressures
teeth grinding
Tolerance
Build-up
develops rapidly after a single use
Reset
7–14 days for baseline
Tolerance Decay
Full tolerance
6h
Half tolerance
7d
Baseline
~14d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Estimates inferred from classical psychedelic patterns (psilocybin/LSD) and user reports; quality anecdotal. Avoid redosing to chase effects during the same session due to tolerance spikes and unpredictability.
Cross-Tolerances
Effects
Aggregated from 50 Erowid experience reports
Positive Effects 10
Music Enhancement
52.0%
70%
Color Enhancement
50.0%
70%
Stimulation
46.0%
70%
Tactile Enhancement
44.0%
70%
Empathy
42.0%
70%
Introspection
32.0%
70%
Euphoria
32.0%
70%
Focus Enhancement
20.0%
70%
Body High
18.0%
70%
Creativity Enhancement
6.0%
70%
Adverse Effects 9
Anxiety
48.0%
70%
Nausea
32.0%
70%
Muscle Tension
30.0%
70%
Confusion
28.0%
70%
Jaw Clenching
14.0%
70%
Pupil Dilation
8.0%
70%
Sweating
6.0%
70%
Increased Heart Rate
6.0%
70%
Motor Impairment
6.0%
70%
Combinations
Cross-Check 4-AcO-DET with another substanceTrip Reports
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
This was my second time on 4-AcO-DET and only a few days since my last trip. Last time I noticed a strong spiritual component to the drug which I wasn't really prepared to make use of. This time, I decided that I would get the most of that. A couple hours before I took it, I spent some time doing some magic.
I have taken 4-AcO-DET twice now. Both times were quite a contrasting experience. The first time I decided to ingest a 7.5 mg dose to get a feeling for the substance, the second time I decided to jump up to 15 mg. The feeling experience is one a exuberance and grandeur. I find to be almost sexual in nature.
February 7th, 2003 This week my roommate left the country for a family emergency, so my partner and I figured we should take advantage of the empty house to evaluate a very rare and obscure psychedelic I recently managed to acquire.
When I first began to investigate psychedelic research chemicals, I rather quickly filed away 4-HO-DET and its acetate ester into a lesser category of drugs, perhaps something of interest only to the most dedicated psychonauts or molecule collectors.
I was in a good mood, and I haven't tried to connect with psychedelics for about eight months, nor have I done anything at all in five months. I feel very convinced that I got a strong psyche, and that I was well prepared of entering the psychedelic world again.
Background: I've done a number of other psychedelics -- LSD, shrooms, 5-MEO-DIPT (foxy), 5-MEO-DMT, 2-CT-7, ketamine as well as most other recreational drugs. I am female, weigh about 115 lbs, and have a fast metabolism. This was my first time trying 4-AcO-DET.
My bottle of 4-aco-DET is almost gone. All the stuff is on the walls of the bottle and stuck to the bottom. It looks yellow. So I said fuck it. I used water to wash it out and I dumped it in orange juice. And as I am about to do what I just typed above I will be back when I am tripping. Lets see what happens.
Bluelight Reference Guide
Tryptamines The Big & Dandy 4-AcO-DET Thread
i've been researching 4 ACO DET and was just wondering if anybody else has any experience? is it that much like shrooms as alot of reports portray?
Read full thread on Bluelight →
4-AcO-DET's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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