Home
    Disclaimer
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-AcO-DET

    Aliases: Ethacetin, Ethylacybin, 4-acetoxy-det

    Categories

    Psychedelic Research-chemical
    4-AcO-DET structure

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    4-AcO-DET is a rare psychedelic tryptamine first synthesized by Albert Hofmann in 1958. It is believed to act as a prodrug for 4-HO-DET (ethocin). Effects are similar to psilocin, though some users report it being more stimulating and anxiety-inducing than other 4-substituted tryptamines. Visual geometry is described as more similar to LSD or 2C-B than to 4-AcO-DMT, with an artificial or synthetic aesthetic quality. There is very limited research on its toxicity and long-term safety profile.

    Perspectives

    “4-AcO-DET is a short trip. It's less introspective and more outrospective. You find yourself hyperanalyzing everything.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 10-15mg 15-20mg 20-35mg 35mg+
    Smoked 5-10mg - - -
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects
    Oral 19-60 min 60-90 min 1.5-3.0 hrs 1.0-2.0 hrs 2.0-4.0 hrs
    Smoked 0 min 4-10 min 10-19 min 19-40 min 30-60 min

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline
    Cross-tolerance
    LSD Psilocybin Psilocin Mescaline DMT 5-MeO-DMT 2C-B 2C-E

    Effects TheDrug.Wiki PsychonautWiki

    Positive
    • Stimulation
    Negative
    • Nausea
    • Pupil dilation
    • Headache
    • Stomach cramp
    • Runny nose
    • Watery eyes
    • Bodily pressures
    • Abnormal heartbeat
    • Stomach bloating
    • Teeth grinding
    Neutral
    • Sedation
    • Excessive yawning
    • Difficulty urinating
    • Frequent urination
    • Restless legs
    • Spontaneous bodily sensations
    • Muscle contractions
    • Increased bodily temperature
    • Brightness alteration
    Positive
    • Thought connectivity
    • Emotion enhancement
    • Euphoria
    • Analysis enhancement
    • Novelty enhancement
    • Conceptual thinking
    • Unity and interconnectedness
    • Wakefulness
    • Immersion intensification
    Negative
    • Anxiety
    • Dizziness
    • Delusion
    • Memory suppression
    Neutral
    • Time distortion
    • Depth perception distortions
    • Perspective distortion
    • Perception of predeterminism
    • Thought loop
    • Perception of interdependent opposites
    • Enhancement and suppression cycles
    • Personal bias suppression
    • Emotion intensification
    Positive
    • Visual enhancement
    • Color enhancement
    • Pattern recognition enhancement
    • Tracers
    • Visual acuity enhancement
    • Increased music appreciation
    • Color shifting
    • Auditory acuity enhancement
    Negative
    • Dehydration
    • Appetite suppression
    Neutral
    • Internal hallucination
    • Auditory hallucination
    • Auditory distortion
    • Diffraction
    • Symmetrical texture repetition
    • Autonomous entity
    • Drifting
    • After images
    • Perspective hallucination

    Combinations TripSit

    Trip Reports Effect Index

    Shaking a Lot nervewing First Experiment with 4-AcO-DET Josie First Impressions of 4-AcO-DET Natalie My Skin Didn't Look Like This Before Natalie My Second Experience with 4-AcO-DET Josie

    Helpful Links

    📘 Experience Reports 📖 Bluelight 📖 PsychonautWiki