4-Bromomethcathinone
Aliases: 4-bmc, 4-bmap, Brephedrone, 4-bromo-n-methylcathinone
Categories
Summary
4-Bromomethcathinone (4-BMC; brephedrone) is a brominated analog of methcathinone with a unique pharmacological profile among stimulant cathinones. Laboratory studies demonstrate it acts primarily as a potent serotonin reuptake inhibitor—approximately 15-fold more effective than methcathinone at SERT—alongside serotonin-norepinephrine-dopamine releasing properties, explaining its reputation for producing empathogenic effects rather than typical stimulation. User reports consistently describe calm euphoria and antidepressant-like feelings at moderate to strong doses, with minimal physical stimulation. Energy Control harm reduction testing (2014-2016) found that only 23.4% of samples sold as 4-BMC were accurately identified, with frequent adulteration or substitution with other cathinones. Halogenated cathinones including 4-BMC possess documented neurotoxic and cytotoxic properties.
Dose Information
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 30-60 min | 30-45 min | 1-2 hrs | 1-2 hrs | 1-3 hrs |
| Insufflated | 10-30 min | 20-30 min | 1-2 hrs | 1-2 hrs | 1-3 hrs |
| Rectal | 15-30 min | 30-45 min | 1-2 hrs | 1-2 hrs | 1-3 hrs |
Tolerance
Effects
- Stimulation
- Physical euphoria
- Increased energy
- Pupil dilation
- Teeth grinding
- Increased perspiration
- Increased heart rate
- Insomnia
- Increased blood pressure
- Increased body temperature
- Euphoria
- Empathy enhancement
- Sociability enhancement
- Emotional enhancement
- Anxiety suppression
- Cognitive euphoria
- Motivation enhancement
- Increased sociability
- Compulsive redosing
- Anxiety
- Motivation suppression
- Talkativeness
- Increased music appreciation
- Music enhancement
- Color enhancement
- Increased libido
- Tactile enhancement
- Disinhibition
- Appetite suppression
- Dehydration
- Vibrating vision
- Spontaneous physical sensations