4-Bromomethcathinone
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: 4-bmc, 4-bmap, Brephedrone, 4-bromo-n-methylcathinone
Summary
4-Bromomethcathinone (4-BMC; brephedrone) is a brominated analog of methcathinone with a unique pharmacological profile among stimulant cathinones. Laboratory studies demonstrate it acts primarily as a potent serotonin reuptake inhibitor—approximately 15-fold more effective than methcathinone at SERT—alongside serotonin-norepinephrine-dopamine releasing properties, explaining its reputation for producing empathogenic effects rather than typical stimulation. User reports consistently describe calm euphoria and antidepressant-like feelings at moderate to strong doses, with minimal physical stimulation.
Dose Information
Dose basis. Ranges are compiled from user reports (Bluelight/Reddit) and analogy to other ring-substituted cathinones; inter-batch variability and frequent mis-selling warrant conservative dosing and reagent/drug checking first. Based on user reports; nasal use increases local irritation and systemic side-effects compared with oral; start very low if used at all. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-75mg | 75-150mg | 150-250mg | 250mg+ |
| Insufflated | 20-40mg | 40-80mg | 80-120mg | 120mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-60 min | 30-45 min | 1-2 hrs | 1-2 hrs | 3-5.75 hrs |
| Insufflated | 10-30 min | 20-30 min | 1-2 hrs | 1-2 hrs | 2.5-5 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria, sensory enhancement, and stimulation with moderate empathy
Strong euphoria and anxiety/jitters with mild stimulation, low focus
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 4-Bromomethcathinone there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
4-Bromomethcathinone Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 20-30 · light 50-75 · common 75-150 · strong 150-250 · heavy 250+ Insufflated dose (mg): threshold 10 · light 20-40 · common 40-80 · strong 80-120 · heavy 120+ Oral duration: onset 0.5-1h · come-up 30-45m · peak 1-2h · offset 1-2h · total 3-5.75h · after-effects 1-3h Insufflated duration: onset 10-30m · come-up 20-30m · peak 1-2h · offset 1-2h · total 2.5-5h · after-effects 1-3h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 112.5 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Anecdotal patterns suggest noticeable acute tolerance after a session, partial recovery by ~3–7 days, and return to baseline within ~2–4 weeks. Given serotonergic mechanism and para‑halogenation toxicity concerns, longer spacing (≥6–8 weeks) is prudent despite limited direct data.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Increased energy
- Pupil dilation
- Teeth grinding
- Increased perspiration
- Increased heart rate
- Insomnia
- Increased blood pressure
- Increased body temperature
- Euphoria
- Empathy enhancement
- Sociability enhancement
- Emotional enhancement
- Anxiety suppression
- Cognitive euphoria
- Motivation enhancement
- Increased sociability
- Compulsive redosing
- Anxiety
- Motivation suppression
- Talkativeness
- Increased music appreciation
- Music enhancement
- Color enhancement
- Increased libido
- Tactile enhancement
- Disinhibition
- Appetite suppression
- Dehydration
- Vibrating vision
- Spontaneous physical sensations
Combinations
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