4-Bromomethcathinone
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: 4-bmc, 4-bmap, Brephedrone, 4-bromo-n-methylcathinone
Summary
4-Bromomethcathinone (4-BMC; brephedrone) is a brominated analog of methcathinone with a unique pharmacological profile among stimulant cathinones. Laboratory studies demonstrate it acts primarily as a potent serotonin reuptake inhibitor—approximately 15-fold more effective than methcathinone at SERT—alongside serotonin-norepinephrine-dopamine releasing properties, explaining its reputation for producing empathogenic effects rather than typical stimulation. User reports consistently describe calm euphoria and antidepressant-like feelings at moderate to strong doses, with minimal physical stimulation.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-75mg | 75-150mg | 150-250mg | 250mg+ |
| Insufflated | 20-40mg | 40-80mg | 80-120mg | 120mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 20-45 min | 1-2 hrs | 1-2 hrs | 3-5 hrs |
| Insufflated | 5-10 min | 1-2 hrs | 1-2 hrs | 3-5 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria, sensory enhancement, and stimulation with moderate empathy
Strong euphoria and anxiety/jitters with mild stimulation, low focus
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Anecdotal patterns suggest noticeable acute tolerance after a session, partial recovery by ~3–7 days, and return to baseline within ~2–4 weeks. Given serotonergic mechanism and para‑halogenation toxicity concerns, longer spacing (≥6–8 weeks) is prudent despite limited direct data.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Increased energy
- Pupil dilation
- Teeth grinding
- Increased perspiration
- Increased heart rate
- Insomnia
- Increased blood pressure
- Increased body temperature
- Euphoria
- Empathy enhancement
- Sociability enhancement
- Emotional enhancement
- Anxiety suppression
- Cognitive euphoria
- Motivation enhancement
- Increased sociability
- Compulsive redosing
- Anxiety
- Motivation suppression
- Talkativeness
- Increased music appreciation
- Music enhancement
- Color enhancement
- Increased libido
- Tactile enhancement
- Disinhibition
- Appetite suppression
- Dehydration
- Vibrating vision
- Spontaneous physical sensations
Combinations
Cross-Check 4-Bromomethcathinone with another substanceHelpful Links
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