MDMA
Aliases: E, X, Md, Xtc, Emma, molly, ecstasy, adam, mandy
Categories
Summary
3,4-Methylenedioxymethamphetamine (also known as ecstasy, E, XTC, emma, molly, mandy, pingers, and MDMA) is a classical entactogen substance of the amphetamine class. It is the most well-known and widely-used member of the entactogens, a diverse group that includes MDA, methylone, 4-MMC, and 6-APB. It produces its effects by promoting the release of serotonin, dopamine, and norepinephrine in the brain, particularly serotonin.
Perspectives
“MDMA intrigued me because everyone I asked, who had used it, answered the question, ‘What’s it like?’ in the same way: ‘I don’t know.’ ‘What happened?’ ‘Nothing.’ And now I understand those answers. I too think nothing happened. But something seemed changed. Before the ‘window’ opened completely, I had some somatic effects, a tingling sensation in the fingers and temples—a pleasant sensation, not distracting. However, just after that there was a slight nausea and dizziness similar to a little too much alcohol. All these details disappeared as I walked outside. My mood was light, happy, but with an underlying conviction that something significant was about to happen. There was a change in perspective both in the near visual field and in the distance. My usually poor vision was sharpened. I saw details in the distance that I could not normally see. After the peak experience had passed, my major state was one of deep relaxation. I felt that I could talk about deep or personal subjects with special clarity, and I experienced some of the feeling one has after the second martini, that one is discoursing brilliantly and with particularly acute analytical powers.”
“MDMA is not a drug to trifle with, and requires sensible consideration, including with respect to aftercare.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral BA ~70% | 20-80mg | 80-120mg | 120-150mg | 150mg+ |
| Insufflated | 30-70mg | 70-120mg | 120-165mg | 165mg+ |
| Rectal | 30-70mg | 70-120mg | 120-165mg | 165mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 30-45 min | 15-30 min | 1.5-2.5 hrs | 60-90 min | 12.0-48.0 hrs | 3.0-5.0 hrs |
| Insufflated | 4-15 min | 10-19 min | 1.0-2.0 hrs | 60-90 min | 12.0-48.0 hrs | 3.0-5.0 hrs |
| Rectal | 19-70 min | - | 3.0-5.0 hrs | - | 1.0-72.0 hrs | 3.0-5.0 hrs |
Tolerance
Effects
- Physical Euphoria
- Stimulation
- Physical euphoria
- Pupil Dilation
- Teeth Grinding
- Increased Heart Rate
- Temperature Regulation Suppression
- Nausea
- Teeth grinding
- Increased heart rate
- Cognitive Euphoria
- Empathy Enhancement
- Affection Enhancement
- Sociability Enhancement
- Anxiety Suppression
- Emotion Enhancement
- Motivation Enhancement
- Motivation enhancement
- Anxiety
- Time Distortion
- Tactile Enhancement
- Increased Music Appreciation
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Disinhibition
- Dehydration
- Light sensitivity
- Appetite suppression
- Spontaneous physical sensations
Combinations
Trip Reports
PiHKAL / TiHKAL
“MDMA intrigued me because everyone I asked, who had used it, answered the question, ‘What’s it like?’ in the same way: ‘I don’t know.’ ‘What happened?’ ‘Nothing.’ And now I understand those answers. I too think nothing happened. But something seemed changed. Before the ‘window’ opened completely, I had some somatic effects, a tingling sensation in the fingers and temples—a pleasant sensation, not distracting. However, just after that there was a slight nausea and dizziness similar to a little too much alcohol. All these details disappeared as I walked outside. My mood was light, happy, but with an underlying conviction that something significant was about to happen. There was a change in perspective both in the near visual field and in the distance. My usually poor vision was sharpened. I saw details in the distance that I could not normally see. After the peak experience had passed, my major state was one of deep relaxation. I felt that I could talk about deep or personal subjects with special clarity, and I experienced some of the feeling one has after the second martini, that one is discoursing brilliantly and with particularly acute analytical powers.”