Summary
4-EMC is the ethyl homologue of 4-MEC and a positional analogue of mephedrone. Human data are limited to user reports and forensic case studies. Users report rapid euphoric stimulant and entactogenic effects with heightened sociability, tactile enhancement and sexual stimulation. Common adverse effects include vasoconstriction, tachycardia, bruxism, mydriasis and hyperthermia. Heavy or repeated dosing often results in severe jaw tension, insomnia, anxiety and next-day dysphoria.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-100mg | 100-200mg | 200mg | 200mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 10-40 min | 20-45 min | 1-2 hrs | 1-2 hrs | 2-8 hrs | 180-0 min |
| Insufflated | 2-5 min | 5-15 min | 1-2 hrs | 1-2 hrs | 2-8 hrs | 180-0 min |
| Rectal | 5-15 min | 15-30 min | 1-2 hrs | 1-2 hrs | 2-8 hrs | 180-0 min |
| Intravenous | 0-1 min | 1-2 min | 1-2 hrs | 1-2 hrs | 2-8 hrs | 180-0 min |
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Effects
Positive
- Stimulation
- Increased energy/alertness
Negative
- Nystagmus
- Bruxism
- Teeth grinding
- Muscle tension
- Vasoconstriction
- Increased perspiration
- Increased heart rate
- Restlessness
- Insomnia
- Weight loss
- Sweating
- Decreased need for sleep
- Decreased appetite
- Disturbed sleep patterns
- Itchiness
Positive
- Euphoria
- Enhanced sociability
- Empathy enhancement
- Increased sociability
- Mood lift
Negative
- Anxiety
- Compulsive redosing
- Motivation suppression
- Depression
- Aggressiveness
- Talkativeness
- Excessive talking
- Moodiness
Positive
- Tactile enhancement
- Increased libido
- Visual enhancement
- Color enhancement
- Increased music appreciation
Negative
- Appetite suppression
- Dehydration
- Light sensitivity
- Increased sexuality
- Visual and auditory hallucinations