4-EPD
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: P-epd, 4-ethylpentedrone, Para-ethyl pentedrone, 4-ethyl-alpha-methylamino-valerophenone
Summary
4-EPD is a ring-ethyl analogue of pentedrone first detected in European drug-checking samples in 2018. Toxicological information is sparse; a handful of fatal intoxications have been documented, usually with poly-drug use. Acute risks mirror those of other potent cathinones: tachycardia, hypertension, hyperthermia, rhabdomyolysis, hyponatremia from excessive water intake, acute psychosis, and serotonin syndrome when mixed with serotonergics.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | 10-20mg | 20-30mg | 30-50mg | 50mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 20-45 min | 30-90 min | 1-2 hrs | 1-3 hrs |
| Insufflated | 5-30 min | 30-90 min | 1-2 hrs | 1-3 hrs |
| Rectal | 5-15 min | 30-90 min | 1-2 hrs | 1-3 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiety/jitters with moderate euphoria, mild focus, low stimulation
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Increased heart rate
- Teeth grinding
- Vasoconstriction
- Insomnia
- Pupil dilation
- Nausea
- Elevated blood pressure
- Sedation
- Decreased appetite
- Euphoria
- Motivation enhancement
- Increased sociability
- Focus enhancement
- Empathy enhancement
- Cognitive euphoria
- Compulsive redosing
- Anxiety
- Anxiolysis or Anxiety
- Time distortion
- Tactile enhancement
- Color enhancement
- Increased music appreciation
- Brightened colour
- Appetite suppression
- Disinhibition
- Light sensitivity
- Dehydration
- Dulled perception
- Drifting
Combinations
Cross-Check 4-EPD with another substanceHelpful Links
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