4-EPD
Aliases: P-epd, 4-ethylpentedrone, Para-ethyl pentedrone, 4-ethyl-alpha-methylamino-valerophenone
Categories
Summary
4-EPD is a ring-ethyl analogue of pentedrone first detected in European drug-checking samples in 2018. Toxicological information is sparse; a handful of fatal intoxications have been documented, usually with poly-drug use. Acute risks mirror those of other potent cathinones: tachycardia, hypertension, hyperthermia, rhabdomyolysis, hyponatremia from excessive water intake, acute psychosis, and serotonin syndrome when mixed with serotonergics. Weigh doses on a 0.001 g scale and perform an allergy test under 2 mg. Redosing markedly prolongs stimulation and increases vasoconstriction—limit to one redose if at all.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | 10-20mg | 20-30mg | 30-50mg | 50mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|
| Oral | 20-45 min | 30-90 min | 1-2 hrs | 2-8 hrs | 60-0 min |
| Insufflated | 5-30 min | 30-90 min | 1-2 hrs | 2-8 hrs | 60-0 min |
| Rectal | 5-15 min | 30-90 min | 1-2 hrs | 2-8 hrs | 60-0 min |
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Effects
Positive
- Stimulation
Negative
- Increased heart rate
- Teeth grinding
- Vasoconstriction
- Insomnia
- Pupil dilation
- Nausea
- Elevated blood pressure
- Sedation
- Decreased appetite
Positive
- Euphoria
- Motivation enhancement
- Increased sociability
- Focus enhancement
- Empathy enhancement
- Cognitive euphoria
Negative
- Compulsive redosing
- Anxiety
- Anxiolysis or Anxiety
- Time distortion
Positive
- Tactile enhancement
- Color enhancement
- Increased music appreciation
- Brightened colour
Negative
- Appetite suppression
- Disinhibition
- Light sensitivity
- Dehydration
- Dulled perception
- Drifting