4-EPD Stats & Data
P-epd
4-ethylpentedrone
Para-ethyl pentedrone
4-ethyl-alpha-methylamino-valerophenone
Chemical Class
Cathinone
Psychoactive Class
Stimulant
Receptor Profile
Receptor Actions
Inhibitors
Dopamine-norepinephrine reuptake inhibitor (NDRI)
Effect Profile
Curated
Stimulant
4.1
Strong anxiety/jitters with moderate euphoria, mild focus, low stimulation
Stimulation / Energy×3
3
Euphoria / Mood Lift×2
7
Focus / Productivity×2
5
Anxiety / Jitters×1
10
Based on reports from:
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Full tolerance
1h
Half tolerance
4d
Baseline
~5d
References
Cited References
- Backberg, Helander et al. Identification of 4-ethylpentedrone in acute intoxications, Sweden 2018-2020
- EMCDDA Early-Warning System report: 4-Ethylpentedrone (4-EPD) 2021
- Global Drug Survey 2023 - Cathinone section (self-reported effects and harms)
- PubChem: 163193057
- Reddit: r/researchchemicals - User experience compilation on 4-EPD (accessed 2025-03-29)
- Trost et al. Fatal intoxication involving 4-ethylpentedrone documented by high-resolution mass spectrometry (Forensic Sci Int, 2022)