T= 0 = 01.05 am Setting: relaxed, at home, secure environment. The time of day was not optimal, but the time was available. Setting: I am not worried about the effects of this relatively little known material as I have read a few accounts of it and had tried taking in combination with other stimulants before with no al...
4-FMC
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 4 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 4 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
Aliases: Drone, 4f-mcat, Flephedrone, Fpephedrone, 4-fluoromethcathinone, 4fmc
Summary
Pentedrone is a Schedule I controlled substance in the United States and is illegal in many countries. The toxicity and long-term health effects have not been studied in scientific contexts, and exact toxic dosage is unknown. Use accurate milligram scales for dosing.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-100mg | 100-150mg | 150-200mg | 200mg+ |
| Insufflated | 25-40mg | 50-100mg | 100-150mg | 150mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 20-40 min | 30-60 min | 1-2 hrs | 30-60 min |
| Insufflated | 5-10 min | 15-30 min | 30-90 min | 30-60 min |
Effect Profile
3 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Empathogen
7.7
Intense
8/10
Strong euphoria and sensory enhancement with moderate empathy, mild stimulation
Empathy / Social Openness
×3
7
empathy enhancement
sociability enhancement
increased sociability
Euphoria / Mood Elevation
×2
10
physical euphoria
euphoria
cognitive euphoria
mood lift
Stimulation
×1
5
stimulation
teeth grinding
increased heart rate
Sensory Enhancement
×1
8
tactile enhancement
spontaneous tactile sensations
increased libido
Stimulant
4.9
Moderate+
5/10
Strong euphoria and anxiety/jitters with mild focus, low stimulation
Stimulation / Energy
×3
3
stimulation
Euphoria / Mood Lift
×2
10
physical euphoria
euphoria
cognitive euphoria
mood lift
motivation enhancement
Focus / Productivity
×2
5
focus enhancement
motivation enhancement
Anxiety / Jitters
×1
10
anxiety
paranoia
teeth grinding
increased heart rate
bruxism
vasoconstriction
+1 more
Based on reports from:
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Tolerance Decay
Full tolerance
2d
Half tolerance
7d
Baseline
~28d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Tolerance to entactogenic/stimulant effects appears to build rapidly across a single day and decays over 1–6 weeks. Values are rough, inferred from user reports for short‑acting cathinones; data quality is anecdotal.
Cross-Tolerances
Effects
Positive
- Stimulation
- Physical euphoria
- Spontaneous tactile sensations
- Increased energy/alertness
Negative
- Teeth grinding
- Vasoconstriction
- Increased heart rate
- Insomnia
- Weight loss
- Sweating
- Bruxism
- Difficulty urinating
- Decreased need for sleep
- Decreased appetite
- Disturbed sleep patterns
- Itchiness
Positive
- Euphoria
- Empathy enhancement
- Sociability enhancement
- Motivation enhancement
- Cognitive Euphoria
- Focus Enhancement
- Increased sociability
- Mood lift
Negative
- Anxiety
- Compulsive redosing
- Paranoia
- Aggressiveness
- Time distortion
- Excessive talking
- Moodiness
Positive
- Increased libido
- Increased music appreciation
- Tactile enhancement
Negative
- Disinhibition
- Dehydration
- Appetite Suppression
- Appetite suppression
- Spontaneous Physical Sensations
- Increased sexuality
- Visual and auditory hallucinations
Combinations
Cross-Check 4-FMC with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 3 reports 3 neutral visit
First off, I've experienced legitimate Mephedrone previously on two occasions and since then various Mephedrone replacements. I acquired the 4-FMC with the hope that it might mimic some of the effects of 4-MMC, I'd previously taken 4-FMC from a different source and found it quite speedy but lacking entactogenically.
Methedrone is soon to be scheduled as a class A drug. A successor, Flephedrone, aka 4-FMC or simply 'Flephe' amongst users, was introduced here last week, though it has been available elsewhere internationally. As of yet uncertain if it will catch on. I've read some mixed reviews so far.
4-FMC's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 4-FMC? Let us know. Reports are reviewed by moderators — this is not posted publicly.