I have now experimented with 30mg, 60mg and 90mg doses of pFPP. Generally I find it hits you within 30-45minutes on an empty stomach, I ate a full pizza (and drank coke) after dosing 90mg I felt a little weird in the stomach but i didn’t throw it up.
4-FPP
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: Pfpp, Fluoperazine, Flipiperazine, Para-fluorophenylpiperazine
Summary
4-FPP was first identified as a urinary metabolite of the sedative niaprazine in 1982 and subsequently sold (2003-2008) in New Zealand "party pills" together with BZP under brand names including "The Big Grin," "Mashed," and "Extreme Beans." In vitro, it is a high-efficacy 5-HT1A agonist (Ki ≈ 11 nM), moderate 5-HT2A/2C partial agonist, and weak SERT/NET releaser. DAT activity is negligible, explaining its low stimulant euphoria compared to BZP. Subjectively, it produces light empathic warmth, mild color enhancement/tracers, and prominent vasoconstrictive "head pressure." Nausea, migraine-like headaches, myalgia, and anxiety are common above ~100 mg.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 20-40mg | 40-80mg | 80-150mg | 150mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 15-45 min | 30-60 min | 1-3 hrs | 1-2 hrs | 4-8 hrs |
| Insufflated | 5-15 min | 15-30 min | 1-3 hrs | 1-2 hrs | 4-8 hrs |
| Rectal | 10-20 min | 20-40 min | 1-3 hrs | 1-2 hrs | 4-8 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
2.1
Light
2/10
Strong body load with mild visuals
Visual Intensity
×3
5
color enhancement
tracers
visual distortions
Headspace Depth
×3
0
Auditory Effects
×1
0
Body Load / Somatic Effects
×1
8
vasoconstriction
nausea
muscle tension
teeth grinding
Empathogen
4.1
Moderate
4/10
Moderate stimulation with mild euphoria, low empathy and sensory enhancement
Empathy / Social Openness
×3
3
empathy enhancement
Euphoria / Mood Elevation
×2
5
euphoria
mood lift
Stimulation
×1
7
physical stimulation
stimulation
teeth grinding
Sensory Enhancement
×1
3
color enhancement
Stimulant
4.0
Moderate
4/10
Strong anxiety/jitters with moderate stimulation, mild euphoria
Stimulation / Energy
×3
7
physical stimulation
stimulation
alertness enhancement
Euphoria / Mood Lift
×2
5
euphoria
mood lift
Focus / Productivity
×2
0
Anxiety / Jitters
×1
9
anxiety
teeth grinding
vasoconstriction
muscle tension
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 4-FPP there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
⬇ Download import file
Import this file as custom substances
and you get "4-FPP (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Name
4-FPP
Unit
mg
Description
4-FPP Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 20-40 · common 40-80 · strong 80-150 · heavy 150+ Insufflated dose: threshold 5 Rectal dose: threshold 10 Oral duration: onset 15-45m · come-up 0.5-1h · peak 1-3h · offset 1-2h · total 4-8h · after-effects 2-12h Insufflated duration: onset 5-15m · come-up 15-30m · peak 1-3h · offset 1-2h · total 4-8h · after-effects 2-12h Rectal duration: onset 10-20m · come-up 20-40m · peak 1-3h · offset 1-2h · total 4-8h · after-effects 2-12h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 60 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops rapidly after a single use
Reset
7–14 days for baseline
Tolerance Decay
Full tolerance
2d
Half tolerance
7d
Baseline
~14d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Tolerance and cross-tolerance estimates are anecdotal and extrapolated from related phenylpiperazines and serotonergic empathogens; space uses by at least 2–3 weeks to reduce blunting and after-effects.
Cross-Tolerances
Effects
Positive
- Stimulation
- Physical stimulation
Negative
- Pupil Dilation
- Vasoconstriction
- Muscle Tension
- Teeth Grinding
- Nausea
- Headache
- Lethargy
- Brightness Alteration
Positive
- Empathy Enhancement
- Euphoria
- Alertness enhancement
- Mood lift
Negative
- Anxiety
- Dysphoria
- Drowsiness
- Talkativeness
- Feelings of Impending Doom
Positive
- Color Enhancement
- Tracers
Negative
- Light sensitivity
- Appetite Suppression
- Decreased Libido
- Dehydration
- Closed-Eye Visuals
- Visual Drifting
- Perception of Bodily Heaviness
- Visual distortions
Combinations
Cross-Check 4-FPP with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Bluelight 5 threads 4 neutral 1 cautionary visit
Am Afraid that I cannot tell the dose as the Pfpp I had was in tablet form 50mg tablets . the first one I took was at home with a mate they had to rush away and it left me watching fear and loathing . I felt peaceful and calm. the Nausea was a bit annoying but okay.
I ordered some pFPP (p-Fluorophenylpiperazine) online and when it arrived I didnt really know what to expect. I carefully measured out 20mgs of the off white powder into a glass of water and stired. It gave the water a very bitter taste but the taste was bearable. at 12.20 I drank down the pfpp and water.
I took between 20 and 40mg (threshold dose is 30mg so I hear) You can not take too much or you will be very uncomfortable. I found it to be a very interesting compound, although it had more evident negative side effects than MDxx, also a little milder for those of us who have worn our seratonin out.
Before: Good pills are hard to come by these days so I figured if I am going to be stuck with pipes right now I should know what I am getting. I did a ton of research on party pills, legal highs, and pretty much anything to do with the different types of piperizines.
4-FPP's nerd page
Pharmacology, chemical data, effect profiles, and more
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