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    4-HO-EPT molecular structure

    4-HO-EPT Stats & Data

    Psychedelic Research-chemical
    Eprocin
    PubChem CID 138454310
    NPS DataHub
    MW246.35
    FormulaC15H22N2O
    IUPAC3-{2-[Ethyl(propyl)amino]ethyl}-1''H''-indol-4-ol
    SMILESCCCN(CC)CCc1cnc2cccc(O)c12
    InChIKeyJQELEPKHBXEAHR-UHFFFAOYSA-N
    Tryptamines; 2020/5.1 Indol-3-alkylamine; 2021/5.1 Indol-3-alkylamine; 2022/5.1 Indol-3-alkylamine
    Chemical Class Tryptamine
    Psychoactive Class Psychedelic

    Pharmacology

    DrugBank

    Receptor Profile

    Receptor Actions

    Agonists
    5-HT2A receptor partial agonist
    5-HT2B receptor agonist
    5-HT2C receptor agonist

    Toxicity

    PsychonautWiki

    The toxicity and long-term health effects of recreational 4-HO-EPT use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 4-HO-EPT is a research chemical with very little history of human usage. Anecdotal evidence from people within the community who have tried 4-HO-EPT suggests that there are no negative health effects attributed to simply trying the it by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). [https://www.google.com/ Independent research] should always be done to ensure that a combination of two or more substances is safe before consumption. It is strongly recommended that one use harm reduction practices when using this substance.

    Effect Profile

    Curated + 8 Reports
    Psychedelic 8.1

    Strong visuals and auditory effects with moderate headspace, mild body load

    Visual Intensity×3
    10
    Headspace Depth×3
    7
    Auditory Effects×1
    8
    Body Load / Somatic Effects×1
    4
    Based on reports from:
    Effect Index Tense and Restless — froggie Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki 4-HO-EPT

    Duration Timeline

    Bluelight
    Onset Comeup Peak Offset After Effects
    Oral
    30 minutes - 1.0 hours
    30-40 minutes
    1-2 hours
    1-2 hours
    2-4 hours
    Total: 4-8 hours
    Smoked
    1-4 minutes
    4-10 minutes
    15-30 minutes
    30 minutes - 1.0 hours
    1-2 hours
    Total: 4-8 hours

    Community Effects

    TripSit
    Positive
    euphoria visual enhancement stimulation relaxation sedation
    Negative
    headache tachycardia

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    LSD
    80% ●○○
    Psilocybin
    85% ●○○
    Psilocin
    85% ●○○
    Mescaline
    65% ●○○
    DMT
    85% ●○○
    5-MeO-DMT
    85% ●○○
    2C-B
    65% ●○○
    2C-E
    65% ●○○

    Experience Report Analysis

    Erowid
    8 Reports
    2016–2022 Date Range
    7 With Age Data
    15 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 8 experience reports (8 Erowid)

    8 Reports
    15 Effects Detected
    7 Positive
    6 Adverse
    2 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 7

    Euphoria 100.0% 70%
    Color Enhancement 87.5% 70%
    Music Enhancement 87.5% 70%
    Body High 75.0% 70%
    Stimulation 62.5% 70%
    Introspection 50.0% 70%
    Focus Enhancement 37.5% 70%

    Adverse Effects 6

    Confusion 50.0% 70%
    Headache 50.0% 70%
    Sweating 37.5% 70%
    Muscle Tension 37.5% 70%
    Anxiety 37.5% 70%
    Nausea 37.5% 70%

    Real-World Dose Distribution

    62K Doses

    From 16 individual dose entries

    Oral (n=15)

    Median: 45.0mg 25th: 28.5mg 75th: 50.0mg 90th: 71.0mg
    mg/kg median: 0.405 mg/kg 75th: 0.512

    Form / Preparation

    Most common forms and preparations reported

    Read full reports on Erowid →

    Legal Status

    Country Status Notes
    Germany 4-HO-EPT is controlled under the NpSG ( New Psychoactive Substances Act ) as of July 18, 2019. Production and import with the aim to place it on the market, administration to another person, placing it on the market and trading is punishable. Possession is illegal but not punishable. The legislator considers it possible that orders of 4-HO-EPT are punishable as an incitement to place it on the market.
    Switzerland 4-HO-EPT is not controlled under Buchstabe A, B, C and D. It could be considered legal.
    United Kingdom 4-HO-EPT is illegal in the United Kingdom as a result of the Psychoactive Substances Act of 2016.
    United States 4-HO-EPT may be considered an analogue of psilocin, which is a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption would be illegal under the Federal Analogue Act.

    References

    Data Sources

    Cited References

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