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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-HO-EPT

    Aliases: Eprocin

    Psychedelic Research-chemical

    Summary TheDrug.Wiki TripSit PsychonautWiki

    4-HO-EPT is a novel research chemical with very little history of human use before 2016 and almost no scientific research on its pharmacology, metabolism, or toxicity. Unlike more visual tryptamines, it primarily enhances colors with a neon quality rather than producing strong visual distortions. Users report a strong euphoric body high sometimes compared to opiates, with a generally light and positive mindset.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 15-20mg 30-40mg 40-60mg 50mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-60 min 30-40 min 1-2 hrs 1-2 hrs 2-4 hrs 4-8 hrs
    Smoked 1-4 min 4-10 min 15-30 min 30-60 min 1-2 hrs 4-8 hrs

    Effect Profile

    8 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.1
    Intense 8/10

    Strong visuals and auditory effects with moderate headspace, mild body load

    Visual Intensity ×3
    10
    color enhancement tracers drifting pattern recognition enhancement color shifting depth perception distortions +2 more
    Headspace Depth ×3
    7
    conceptual thinking emotion enhancement thought loops personal bias suppression time distortion
    Auditory Effects ×1
    8
    auditory distortion auditory hallucination
    ⚠ Body Load / Somatic Effects ×1
    4
    nausea increased heart rate
    Based on reports from:
    Effect Index Tense and Restless Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki 4-HO-EPT
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Cross-Tolerances

    Lysergamides
    LSD
    80%
    Tryptamines
    Psilocybin
    85%
    Psilocin
    85%
    DMT
    85%
    5-MeO-DMT
    85%
    Phenethylamines
    Mescaline
    65%
    2C-B
    65%
    2C-E
    65%

    Effects Erowid

    Aggregated from 8 Erowid experience reports

    Positive Effects 7

    Euphoria 100.0% 70%
    Color Enhancement 87.5% 70%
    Music Enhancement 87.5% 70%
    Body High 75.0% 70%
    Stimulation 62.5% 70%
    Introspection 50.0% 70%
    Focus Enhancement 37.5% 70%

    Adverse Effects 6

    Confusion 50.0% 70%
    Headache 50.0% 70%
    Sweating 37.5% 70%
    Muscle Tension 37.5% 70%
    Anxiety 37.5% 70%
    Nausea 37.5% 70%

    Combinations TripSit

    Trip Reports Effect Index

    Tense and Restless froggie
    4-HO-EPT's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 TripSit 📖 Bluelight 📖 PsychonautWiki