I just figured I'd provide a report on a very new research chemical that has hardly any information on it. I was a frequent DXM user, and after about 25 trips of 6.5mg/kg average, I found myself unable to get much of anything from the trips. I stopped using it in Feb. 09, and havent touched it since.
4-MeO-PCP
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 6 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
- classified Research-chemical
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 6 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- PubChem toxicity data
- classified Research-chemical
Aliases: Methoxydine, 4-methoxy-pcp, 4meopcp
Summary
4-MeO-PCP is a long-acting dissociative with approximately 70% the potency of PCP. Users have reported substantial differences in active dose; these discrepancies may be partially explained by the presence of unreacted PCC and other impurities in samples sold on the grey market. Use a precise milligram scale for dosing.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 75-100mg | 100-170mg | 170-250mg | 250mg+ |
| Insufflated | 30-75mg | 75-150mg | 150-300mg | 300mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 0.75-2 hrs | 30-90 min | 3-7 hrs | 6-10 hrs | 12-20 hrs |
| Insufflated | 4-15 min | 15-30 min | 3-6 hrs | 3 hrs | 12-18 hrs |
Effect Profile
7 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
6.5
Strong
6/10
Strong auditory effects with moderate visuals, mild headspace, low body load
Visual Intensity
×3
7
internal hallucinations
scenery slicing
environmental cubism
environmental orbism
Headspace Depth
×3
5
conceptual thinking
introspection
time distortion
Auditory Effects
×1
8
auditory distortion
auditory hallucination
Body Load / Somatic Effects
×1
2
nausea
Dissociative
6.6
Strong+
7/10
Strong dissociative depth, mania, motor impairment, and insight
Dissociative Depth
×3
10
consciousness disconnection
depersonalization
derealization
physical disconnection
cognitive disconnection
visual disconnection
+5 more
Mania / Compulsion
×1
10
mania
compulsive redosing
disinhibition
stimulation
Insight / Novel Thought
×2
8
conceptual thinking
introspection
creativity enhancement
immersion enhancement
Motor / Sensory Impairment
×1
10
motor control loss
physical disconnection
tactile suppression
numbness
spatial disorientation
visual disconnection
+1 more
Based on reports from:
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2โ4 weeks for noticeable reduction
Tolerance Decay
Full tolerance
1d
Half tolerance
21d
Baseline
~28d
Acute tolerance: develops within a single session โ the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 7 Erowid experience reports
Positive Effects 2
Euphoria
57.1%
70%
Focus Enhancement
42.9%
70%
Adverse Effects 1
Confusion
71.4%
70%
Combinations
Cross-Check 4-MeO-PCP with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 7 reports 1 positive 6 neutral visit
I tried 4-meo-pcp for the first time last night. The afterglow is still slowing down my intellect at the moment, but I want to write a report while the experience is still somewhat fresh in my mind. I'll make comparisons to ketamine in this report, because I found 4meo to be quite similar.
This was my first time with this chemical, I was expecting something like ketamine, but the come up was incredibly similar to DXM: thoughts became fragmented and speech became difficult.
The universe sent me a free sample of 200 mgs 4-meo-PCP (methoxydine) today. This Methoxydine Powdah is white amorphous crystal shards. About me: 23 year old male, 5ย8, 150 lbs.
I'm at home, in the evening, mostly in my room for the duration of this report. I'm somewhat experienced with infrequent MXE use, taken orally and sublingually in the 25-75mg range over the last two years. Three or four DXM experiences over a decade ago..
I got a free sample of 4-MeO-PCP. My intention is to write a decent report on my experimentation with the substance. This morning I took 300 mg dextromethorphan (pure). This is fairly normal for me. I take this amount 3-4 times on an average week.
So this is my first report but not my first use so i think this chem needs a lil recognition. so after drinking hard and doing adderal for the three days i went home and recovered from New Years. After sleeping almost 20hrs i woke up around 2 in the morning.
Bluelight Reference Guide
The Big & Dandy 4-MeO-PCP Thread 2 - 4-MeO, 4-MeO, wherefore art thou 4-MeO?
Welcome to the Big & dandy 4-MeO-PCP Thread! *Picture and fancy summary to come* previous thread So any new opinions of the drug and not potential presence of poisonous precursor paranoia? (Just asking, not saying don't talk about the PCC thing, it remains a relevant concern)
Read full thread on Bluelight โ
4-MeO-PCP's nerd page
Pharmacology, chemical data, effect profiles, and more
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