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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    5-EAPB

    Aliases: 5eapb

    Psychedelic Stimulant Empathogen Research-chemical

    Summary TheDrug.Wiki TripSit

    Extremely limited human data; doses above 140 mg strongly discouraged. Fatal case reported at ~500 mg combined with MDAI (blood concentration 6.45 mg/L). Acts as monoamine releasing agent with 5-HT2A/5-HT2B agonist properties; chronic use may risk valvular heart disease via 5-HT2B activation.

    Dose Information TheDrug.Wiki TripSit

    ROA Light Common Strong Heavy
    Oral 50-60mg 60-100mg 100-150mg 150mg+
    Insufflated 30-40mg 40-60mg 60-100mg 100mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit

    ROA Onset Comeup Peak Offset After Effects
    Oral 30-60 min 30-60 min 2-3 hrs 1-2 hrs 6-12 hrs
    Insufflated 5-10 min 15-30 min 2-3 hrs 1-2 hrs 6-12 hrs

    Effect Profile

    2 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 3.2
    Light+ 3/10

    Strong auditory effects with moderate body load, mild visuals, low headspace

    Visual Intensity ×3
    4
    colour enhancement tracers
    Headspace Depth ×3
    1
    time distortion
    Auditory Effects ×1
    8
    auditory distortion auditory hallucination
    ⚠ Body Load / Somatic Effects ×1
    7
    temperature regulation suppression teeth grinding increased heart rate sweating
    Empathogen 6.1
    Strong 6/10

    Strong euphoria with moderate sensory enhancement, mild empathy and stimulation

    Empathy / Social Openness ×3
    5
    empathy, affection, and sociability enhancement increased sociability
    Euphoria / Mood Elevation ×2
    8
    cognitive euphoria euphoria mood lift
    Stimulation ×1
    5
    stimulation teeth grinding increased heart rate
    Sensory Enhancement ×1
    7
    tactile enhancement colour enhancement increased libido
    Stimulant 3.2
    Light+ 3/10

    Strong anxiety/jitters and euphoria with low stimulation

    Stimulation / Energy ×3
    3
    stimulation
    Euphoria / Mood Lift ×2
    8
    cognitive euphoria euphoria mood lift
    Focus / Productivity ×2
    0
    ⚠ Anxiety / Jitters ×1
    9
    anxiety teeth grinding increased heart rate sweating
    Based on reports from:
    Erowid Experience Reports PsychonautWiki 5-EAPB
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~21d

    Tolerance data for 5‑EAPB is not formally studied; model reflects community practice with MDMA‑like releasers: marked acute tolerance after one strong session, partial recovery after ~1–2 weeks, closer to baseline by ~4–6 weeks. Confidence low; individual variability high.

    Cross-Tolerances

    MDMA
    60%
    5‑APB/6‑APB
    70%
    Other serotonin releasers
    50%

    Effects TheDrug.Wiki TripSit

    Positive
    • Stimulation
    • Increased energy/alertness
    Negative
    • Pupil dilation
    • Teeth grinding
    • Temperature regulation suppression
    • Increased heart rate
    • Weight loss
    • Sweating
    Neutral
    • Difficulty urinating
    • Decreased need for sleep
    • Decreased appetite
    • Distrubed sleep patterns
    • Bruxia
    Positive
    • Cognitive euphoria
    • Empathy, affection, and sociability enhancement
    • Euphoria
    • Increased sociability
    • Mood lift
    Negative
    • Anxiety
    • Agressiveness
    Neutral
    • Excessive talking
    • Moodiness
    • Time distortion
    Positive
    • Increased music appreciation
    • Tactile enhancement
    • Colour enhancement
    • Bodily control enhancement
    • Increased libido
    • Tracers
    Neutral
    • Increase sexuality
    • Visual and audiotory hallucinations itchiness
    • Auditory hallucination
    • Auditory distortion

    Combinations TripSit

    5-EAPB's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki